PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32817784-8 2020 Conclusions: Our results suggest that opening mitochondrial potassium ATP channels with diazoxide upregulates the expression of STIM1 and Orai1 by de novo synthesis by a mechanism that involves NFkB, c-Fos, and ROS via MAPK/ERK signaling. Diazoxide 88-97 Eph receptor B1 Rattus norvegicus 224-227 23418587-12 2013 Phospho-ERK signals were detected in Connexin43 immunoprecipitates in the Diazoxide-treated astrocytes, but not untreated control samples. Diazoxide 74-83 Eph receptor B1 Rattus norvegicus 8-11 23418587-13 2013 Finally, inhibiting ERK could attenuate the effects of Diazoxide on electrical coupling by 61%. Diazoxide 55-64 Eph receptor B1 Rattus norvegicus 20-23 21186579-10 2006 At the end of reperfusion, compared with Con group, the expression of ERK in myocardium were higher in IP and DP groups (P < 0.01 vs Con), there was no significance between 5-HD and Con group, but 5-HD couldn"t inhibit the expression of ERK induced by diazoxide preconditioning. Diazoxide 255-264 Eph receptor B1 Rattus norvegicus 70-73 21186579-12 2006 CONCLUSION: These results indicated that diazoxide preconditioning could mimic ischemic preconditioning, the activation of ERK expression and the declining of JNK expression involved in diazoxide preconditioning in isolated SHR hearts. Diazoxide 41-50 Eph receptor B1 Rattus norvegicus 123-126 21538163-0 2012 Diazoxide inhibits aortic endothelial cell apoptosis in diabetic rats via activation of ERK. Diazoxide 0-9 Eph receptor B1 Rattus norvegicus 88-91 21538163-8 2012 Diazoxide could significantly enhance phosphorylation of ERK via opening mito K(ATP) channels. Diazoxide 0-9 Eph receptor B1 Rattus norvegicus 57-60 21538163-10 2012 The present studies demonstrate that diazoxide prevents the onset and development of macrovascular disease in OLETF rats by inhibiting apoptosis directly via phosphorylated ERK increase in aorta ECs. Diazoxide 37-46 Eph receptor B1 Rattus norvegicus 173-176