PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6087679-0	1984	Antagonistic effect of theophylline on the adenosine-induced decreased in renin release.	Theophylline	23-35	renin	Canis lupus familiaris	74-79	
2570368-3	1989	Accordingly, we examined the effects of infusions of caffeine and theophylline directly into the renal artery on the increase in renin secretion induced by suprarenal aortic constriction.	Theophylline	66-78	renin	Canis lupus familiaris	129-134	
2570368-7	1989	However, in the non-filtering, beta-adrenoceptor blocked, canine kidney, theophylline markedly increased the renin response to suprarenal aortic constriction.	Theophylline	73-85	renin	Canis lupus familiaris	109-114	
6087679-1	1984	The action of theophylline on the adenosine-induced decrease in renin release was studied in anesthetized dogs.	Theophylline	14-26	renin	Canis lupus familiaris	64-69	
6087679-3	1984	Theophylline (5 mumol/min intrarenally) had no significant effect on GFR or RBF yet produced a significant increase in the release of renin and the fractional excretion of sodium.	Theophylline	0-12	renin	Canis lupus familiaris	134-139	
6087679-7	1984	Theophylline at 5 X 10(-6) mol/min, which stimulates renin release and effectively antagonizes the renal effects of adenosine, had no detectable effect on cAMP measured in renal cortex.	Theophylline	0-12	renin	Canis lupus familiaris	53-58	
6087679-9	1984	These findings demonstrate that theophylline, at concentrations having no effect on cortical cAMP, antagonizes the effect of adenosine on renin release.	Theophylline	32-44	renin	Canis lupus familiaris	138-143	
6087679-10	1984	The results are also consistent with the view that theophylline stimulates renin release by a mechanism other than its action on cAMP.	Theophylline	51-63	renin	Canis lupus familiaris	75-80	
6312554-0	1983	Conditions for augmentation of renin release by theophylline.	Theophylline	48-60	renin	Canis lupus familiaris	31-36	
6312554-3	1983	To examine this hypothesis further the effects on renin release of theophylline, which would maintain high intracellular concentration of cAMP by inhibiting phosphodiesterase, were studied in anesthetized dogs.	Theophylline	67-79	renin	Canis lupus familiaris	50-55	
6312554-4	1983	After inhibiting beta-adrenergic stimulation with propranolol, theophylline increased renin release significantly from 0.7 +/- 0.2 to 1.8 +/- 0.7 micrograms/min at control blood pressure and from 23 +/- 4 to 41 +/- 5 micrograms/min at a renal perfusion pressure of about 50 mmHg.	Theophylline	63-75	renin	Canis lupus familiaris	86-91	
6312554-7	1983	The renin release response to infusion of theophylline at low blood pressure was not enhanced by DB-cAMP infusion.	Theophylline	42-54	renin	Canis lupus familiaris	4-9	
6312554-8	1983	We conclude that arteriolar dilation provides a condition for stimulation of renin release during the theophylline infusion.	Theophylline	102-114	renin	Canis lupus familiaris	77-82	
6312554-9	1983	Theophylline infusion may augment the effect of isoproterenol on renin release by delaying the intracellular degradation of cAMP.	Theophylline	0-12	renin	Canis lupus familiaris	65-70	
214314-3	1978	Theophylline (0.1 mg/kg/min) did not affect renal hemodynamics but caused a slight increase in renin secretion after 30--60 min infusion.	Theophylline	0-12	renin	Canis lupus familiaris	95-100	
214314-4	1978	The combined infusion of glucagon (0.5 microgram/kg/min) with theophylline (0.1 mg/kg/min) increased renin secretion markedly, although it produced renal hemodynamic changes similar to those induced by glucagon alone.	Theophylline	62-74	renin	Canis lupus familiaris	101-106	
214314-6	1978	It is suggested that the increase in renin secretion caused by the combined infusion of glucagon and theophylline resulted mainly from an increase in cyclic AMP in the juxtaglomerular cells, and not from stimulation of beta-adrenoceptors.	Theophylline	101-113	renin	Canis lupus familiaris	37-42	
11299275-11	2001	Thus infusion of the adenosine receptor antagonist theophylline inhibited the suppression of the renin-angiotensin system during acute hypoxia.	Theophylline	51-63	renin	Canis lupus familiaris	97-102	
4401810-0	1972	Stimulation of renin secretion in dogs by theophylline.	Theophylline	42-54	renin	Canis lupus familiaris	15-20