PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9656574-0	1998	[Theophylline reduces serum levels of ECP in vitro].	Theophylline	1-13	ribonuclease A family member 3	Homo sapiens	38-41	
23994670-13	2014	Proton pump inhibitors, antidepressants, theophylline, and cognitive behavioral therapy appear to be useful for the treatment of ECP.	Theophylline	41-53	ribonuclease A family member 3	Homo sapiens	129-132	
23290154-7	2013	A significant decrease in eosinophil count and concentration of eosinophil cationic protein in induced sputum was also seen in the theophylline plus SFC group when compared with the SFC plus placebo group (4.1 +- 2.2% and 6.3 +- 2.7%, 63.6 +- 39.5 mug/L and 89.4 +- 45.6 mug/L, respectively; all p < 0.01).	Theophylline	131-143	ribonuclease A family member 3	Homo sapiens	64-91	
10705222-0	2000	Once-daily theophylline reduces serum eosinophil cationic protein and eosinophil levels in induced sputum of asthmatics.	Theophylline	11-23	ribonuclease A family member 3	Homo sapiens	38-65	
10705222-7	2000	After treatment with theophylline, both serum ECP and the percentage of eosinophils in induced sputum were significantly decreased.	Theophylline	21-33	ribonuclease A family member 3	Homo sapiens	46-49	
9656574-1	1998	Measurement of serum levels of ECP has been widely used for monitoring airway inflammation in bronchial asthma and recently been applied to measure anti-inflammatory effect of theophylline.	Theophylline	176-188	ribonuclease A family member 3	Homo sapiens	31-34	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	34-46	ribonuclease A family member 3	Homo sapiens	27-30	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	34-46	ribonuclease A family member 3	Homo sapiens	175-178	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	34-46	ribonuclease A family member 3	Homo sapiens	175-178	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	108-120	ribonuclease A family member 3	Homo sapiens	27-30	
9656574-2	1998	However, reduced levels of ECP in theophylline-administered patients may express not only in vivo effect of theophylline but also in vitro effect after sampling because serum ECP measures released ECP during coagulation and theophylline has been reported to inhibit eosinophil degranulation in vitro.	Theophylline	108-120	ribonuclease A family member 3	Homo sapiens	27-30	
9656574-3	1998	In order to answer the question, we tested whether theophylline added to blood after sampling reduces measured levels of serum ECP.	Theophylline	51-63	ribonuclease A family member 3	Homo sapiens	127-130	
9656574-6	1998	Theophylline significantly reduced serum ECP in a concentration-dependent manner.	Theophylline	0-12	ribonuclease A family member 3	Homo sapiens	41-44	
9656574-7	1998	Percent reduction of ECP levels at 1 hour of incubation were 11.9%, 18.7%, 22.8%, and 51.7% at theophylline levels of 5, 12.5, 22.5, and 120 micrograms/ml, respectively.	Theophylline	95-107	ribonuclease A family member 3	Homo sapiens	21-24	
9656574-8	1998	Kinetics of serum ECP release was also inhibited in the presence of theophylline.	Theophylline	68-80	ribonuclease A family member 3	Homo sapiens	18-21	
9656574-9	1998	These results suggest that in vitro effect of theophylline on serum ECP levels should be considered when data of serum ECP in patients who take theophylline are interpreted.	Theophylline	46-58	ribonuclease A family member 3	Homo sapiens	68-71	
9656574-9	1998	These results suggest that in vitro effect of theophylline on serum ECP levels should be considered when data of serum ECP in patients who take theophylline are interpreted.	Theophylline	46-58	ribonuclease A family member 3	Homo sapiens	119-122	
9656574-9	1998	These results suggest that in vitro effect of theophylline on serum ECP levels should be considered when data of serum ECP in patients who take theophylline are interpreted.	Theophylline	144-156	ribonuclease A family member 3	Homo sapiens	68-71	
9656574-9	1998	These results suggest that in vitro effect of theophylline on serum ECP levels should be considered when data of serum ECP in patients who take theophylline are interpreted.	Theophylline	144-156	ribonuclease A family member 3	Homo sapiens	119-122	
9461728-0	1997	[The effect of an isotonic solution of theophylline 300 on eosinophil cationic protein levels].	Theophylline	39-51	ribonuclease A family member 3	Homo sapiens	59-86	
9461728-1	1997	UNLABELLED: The aim of the study was to compare the influence of theophylline 300 on eosinophil cationic protein (ECP)level in serum in asthmatic patients Theophylline was given twice a day.	Theophylline	65-77	ribonuclease A family member 3	Homo sapiens	85-112	
9461728-1	1997	UNLABELLED: The aim of the study was to compare the influence of theophylline 300 on eosinophil cationic protein (ECP)level in serum in asthmatic patients Theophylline was given twice a day.	Theophylline	65-77	ribonuclease A family member 3	Homo sapiens	114-117	
9461728-1	1997	UNLABELLED: The aim of the study was to compare the influence of theophylline 300 on eosinophil cationic protein (ECP)level in serum in asthmatic patients Theophylline was given twice a day.	Theophylline	155-167	ribonuclease A family member 3	Homo sapiens	114-117	
8630596-5	1996	Theophylline did not alter lung functions but reduced ECP and EPX/EDN after prolonged treatment.	Theophylline	0-12	ribonuclease A family member 3	Homo sapiens	54-57	
7539697-9	1995	The beta 2-adrenoceptor agonist, salbutamol (1 mumol l-1), which by itself did not substantially influence the two cell responses, only marginally improved the potency of theophylline and IBMX in inhibiting ECP/EDN secretion.	Theophylline	171-183	ribonuclease A family member 3	Homo sapiens	207-210