PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12648218-9 2003 Finally, preincubation of keratinocytes with a polyclonal antibody against the membrane receptor annexin II, blocked the 1alpha,25-dihydroxyvitamin D3-induced activation of extracellular signal regulated kinase 1/2 and c-Jun N-terminal kinase 1. 25-dihydroxyvitamin d3 128-150 mitogen-activated protein kinase 8 Homo sapiens 219-244 12648218-10 2003 Taken together, our results indicate that 1alpha,25-dihydroxyvitamin D3, via binding to the membrane receptor annexin II, induces activation of the phos-phatidylinositol 3-kinase/Ras/MEK/extracellular signal regulated kinase 1/2 and c-Jun N-terminal kinase 1 signal transduction pathway resulting in increased expression of c-Fos, Fra1, and c-Jun, and subsequently increased activator protein 1 DNA binding activity and gene transcription. 25-dihydroxyvitamin d3 49-71 mitogen-activated protein kinase 8 Homo sapiens 233-258