PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17996851-7 2007 Exposure to sorbitol also resulted in cleavage of the nuclear repair enzyme, poly(ADP-ribose) polymerase (PARP) and induced DNA fragmentation in slices. Sorbitol 12-20 poly (ADP-ribose) polymerase 1 Rattus norvegicus 77-104 17996851-7 2007 Exposure to sorbitol also resulted in cleavage of the nuclear repair enzyme, poly(ADP-ribose) polymerase (PARP) and induced DNA fragmentation in slices. Sorbitol 12-20 poly (ADP-ribose) polymerase 1 Rattus norvegicus 106-110 17996851-8 2007 Concomitant treatment with sorbitol and SB202190, a selective p38 inhibitor, prevented the increase in cytosolic cytochrome c, decreased caspase-3 activation, and partially reduced PARP cleavage in a concentration-dependent manner. Sorbitol 27-35 poly (ADP-ribose) polymerase 1 Rattus norvegicus 181-185 15202016-9 2004 In conclusion, PARP is involved in diabetes- and hypoxia-induced VEGF production at post-transcriptional level, downstream from the sorbitol pathway activation and oxidative stress. Sorbitol 132-140 poly (ADP-ribose) polymerase 1 Rattus norvegicus 15-19