PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31780563-10	2020	Thus, sodium arsenite appears to promote SG formation and TDP-43 modifications via oxidative stress, but sorbitol stimulates TDP-43 ubiquitylation and insolubility via a novel pathway(s) independent of SG formation.	Sorbitol	105-113	TAR DNA binding protein	Homo sapiens	125-131	
29630989-7	2018	Furthermore, D-sorbitol - known to induce stress granules and cytoplasmic mislocalization of TDP43 - rescued axonal trafficking phenotypes without signs of TDP43 mislocalization or aggregation formation.	Sorbitol	13-23	TAR DNA binding protein	Homo sapiens	93-98	
21173160-0	2011	TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor.	Sorbitol	41-49	TAR DNA binding protein	Homo sapiens	0-6	
21173160-4	2011	In this study, we establish sorbitol as a novel physiological stressor that directs TDP-43 to stress granules in Hek293T cells and primary cultured glia.	Sorbitol	28-36	TAR DNA binding protein	Homo sapiens	84-90	
34378050-5	2021	We show that sorbitol drives TDP-43 redistribution to the cytoplasm, while arsenite induces the recruitment of cytoplasmic TDP-43 to TIA-1 positive SGs.	Sorbitol	13-21	TAR DNA binding protein	Homo sapiens	29-35	
28510586-4	2017	Here we detail the use of D-sorbitol as an exogenous stressor that causes TDP-43 cleavage in HeLa cells, resulting in a 35 kDa truncated product that accumulates in the cytoplasm within one hour of treatment.	Sorbitol	26-36	TAR DNA binding protein	Homo sapiens	74-80	
28510586-7	2017	Using D-sorbitol as a stressor and caspase activator, we also demonstrate that the A90V variant of TDP-43, which lies adjacent to the caspase cleavage site within the nuclear localization sequence of TDP-43, confers partial resistance against caspase-mediated generation of the 35 kDa cleavage product.	Sorbitol	6-16	TAR DNA binding protein	Homo sapiens	99-105	
28510586-7	2017	Using D-sorbitol as a stressor and caspase activator, we also demonstrate that the A90V variant of TDP-43, which lies adjacent to the caspase cleavage site within the nuclear localization sequence of TDP-43, confers partial resistance against caspase-mediated generation of the 35 kDa cleavage product.	Sorbitol	6-16	TAR DNA binding protein	Homo sapiens	200-206