PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12769600-9 2002 It is now known that this other site is similar to NTE in that it is also sensitive to mipafox but at much higher concentrations. mipafox 87-94 patatin like phospholipase domain containing 6 Gallus gallus 51-54 22503708-2 2012 In this work, we evaluate and characterize the interaction (inhibition, reactivation and "ongoing inhibition") of two model compounds: paraoxon (non-neuropathy-inducer) and mipafox (neuropathy-inducer), with esterases of chicken brain membranes, an animal model, tissue and fractions, where neuropathy target esterase (NTE) was first described and isolated. mipafox 173-180 patatin like phospholipase domain containing 6 Gallus gallus 291-317 22503708-2 2012 In this work, we evaluate and characterize the interaction (inhibition, reactivation and "ongoing inhibition") of two model compounds: paraoxon (non-neuropathy-inducer) and mipafox (neuropathy-inducer), with esterases of chicken brain membranes, an animal model, tissue and fractions, where neuropathy target esterase (NTE) was first described and isolated. mipafox 173-180 patatin like phospholipase domain containing 6 Gallus gallus 319-322 12791540-0 2003 Relative inhibitory potencies of chlorpyrifos oxon, chlorpyrifos methyl oxon, and mipafox for acetylcholinesterase versus neuropathy target esterase. mipafox 82-89 patatin like phospholipase domain containing 6 Gallus gallus 122-148 8812209-1 1996 A method is presented for the isolation of a 155-kDa protein that possesses phenyl valerate hydrolysis activity in the presence of paraoxon but is inhibited by mipafox; the functional definition of neuropathy target esterase (neurotoxic esterase; NTE). mipafox 160-167 patatin like phospholipase domain containing 6 Gallus gallus 198-224 9109545-1 1997 Neuropathy target esterase (NTE) activity is operatively defined in this work as the phenyl valerate esterase (PVase) activity resistant to 40 microM paraoxon but sensitive to 250 microM mipafox. mipafox 187-194 patatin like phospholipase domain containing 6 Gallus gallus 0-26 9109545-1 1997 Neuropathy target esterase (NTE) activity is operatively defined in this work as the phenyl valerate esterase (PVase) activity resistant to 40 microM paraoxon but sensitive to 250 microM mipafox. mipafox 187-194 patatin like phospholipase domain containing 6 Gallus gallus 28-31 9109545-11 1997 The chromatographic pattern and mipafox sensitivity suggest that the different tissues have a different NTE isoform composition. mipafox 32-39 patatin like phospholipase domain containing 6 Gallus gallus 104-107 9413546-2 1997 The esterase activity in particulate forms, resistant to paraoxon and sensitive to mipafox have been implicated in the initiation of organophosphorus-induced delayed polyneuropathy (OPIDP) and is called neuropathy target esterase (P-NTE). mipafox 83-90 patatin like phospholipase domain containing 6 Gallus gallus 203-229 9413546-2 1997 The esterase activity in particulate forms, resistant to paraoxon and sensitive to mipafox have been implicated in the initiation of organophosphorus-induced delayed polyneuropathy (OPIDP) and is called neuropathy target esterase (P-NTE). mipafox 83-90 patatin like phospholipase domain containing 6 Gallus gallus 233-236 9413546-11 1997 In all fractions, except brain soluble fractions, within the paraoxon resistant activity, a mipafox sensitive component was detected that is operationally considered NTE (P-NTE and S-NTE in particulate and soluble fractions, respectively). mipafox 92-99 patatin like phospholipase domain containing 6 Gallus gallus 166-169 9413546-11 1997 In all fractions, except brain soluble fractions, within the paraoxon resistant activity, a mipafox sensitive component was detected that is operationally considered NTE (P-NTE and S-NTE in particulate and soluble fractions, respectively). mipafox 92-99 patatin like phospholipase domain containing 6 Gallus gallus 173-176 9413546-11 1997 In all fractions, except brain soluble fractions, within the paraoxon resistant activity, a mipafox sensitive component was detected that is operationally considered NTE (P-NTE and S-NTE in particulate and soluble fractions, respectively). mipafox 92-99 patatin like phospholipase domain containing 6 Gallus gallus 173-176 7705869-2 1995 The neurotoxic esterase (NTE) activity was significantly inhibited in the brain, spinal cord and platelets of hens treated with mipafox or sarin whereas no change was noticed with parathion treatment. mipafox 128-135 patatin like phospholipase domain containing 6 Gallus gallus 4-23 7671342-1 1995 Neuropathy target esterase (NTE) activity is operatively defined in this paper as the phenyl valerate esterase activity resistant to 40 microM paraoxon but sensitive to 250 microM mipafox. mipafox 180-187 patatin like phospholipase domain containing 6 Gallus gallus 0-26 7671342-1 1995 Neuropathy target esterase (NTE) activity is operatively defined in this paper as the phenyl valerate esterase activity resistant to 40 microM paraoxon but sensitive to 250 microM mipafox. mipafox 180-187 patatin like phospholipase domain containing 6 Gallus gallus 28-31 7705869-2 1995 The neurotoxic esterase (NTE) activity was significantly inhibited in the brain, spinal cord and platelets of hens treated with mipafox or sarin whereas no change was noticed with parathion treatment. mipafox 128-135 patatin like phospholipase domain containing 6 Gallus gallus 25-28 8343992-6 1993 It proved difficult to elute active NTE under non-denaturing conditions, but SDS-PAGE analysis of MNTFP-Sepharose bound proteins eluted with 2% SDS identified a 155 kDa NTE-like protein that bound in a trifluoromethylketone- or mipafox-sensitive but paraoxon-insensitive manner. mipafox 228-235 patatin like phospholipase domain containing 6 Gallus gallus 169-172 8337699-6 1993 These results indicate that NTE inhibition can be detected in neuroblastoma cells, that these cells respond in a manner similar to chicken brain, and that mipafox-induced inhibition of NTE can be decreased in the presence of aldicarb or verapamil. mipafox 155-162 patatin like phospholipase domain containing 6 Gallus gallus 28-31 8337699-6 1993 These results indicate that NTE inhibition can be detected in neuroblastoma cells, that these cells respond in a manner similar to chicken brain, and that mipafox-induced inhibition of NTE can be decreased in the presence of aldicarb or verapamil. mipafox 155-162 patatin like phospholipase domain containing 6 Gallus gallus 185-188 2703698-1 1989 We developed a histochemical method for localizing neurotoxic esterase (NTE), defined as the phenylvalerate (PV)-hydrolyzing esterase that is resistant to 40 microM paraoxon (A) but inactivated by paraoxon plus 50 microM mipafox (B). mipafox 221-228 patatin like phospholipase domain containing 6 Gallus gallus 51-70 1471154-2 1992 At doses of 18-182 micrograms mipafox and 9-110 micrograms DFP, inhibition of neuropathy target esterase (NTE) for the treated segment was over 80%, whereas for the adjacent distal and proximal segments inhibition was under 40%, 15 min after application. mipafox 30-37 patatin like phospholipase domain containing 6 Gallus gallus 78-104 1471154-2 1992 At doses of 18-182 micrograms mipafox and 9-110 micrograms DFP, inhibition of neuropathy target esterase (NTE) for the treated segment was over 80%, whereas for the adjacent distal and proximal segments inhibition was under 40%, 15 min after application. mipafox 30-37 patatin like phospholipase domain containing 6 Gallus gallus 106-109 2703698-1 1989 We developed a histochemical method for localizing neurotoxic esterase (NTE), defined as the phenylvalerate (PV)-hydrolyzing esterase that is resistant to 40 microM paraoxon (A) but inactivated by paraoxon plus 50 microM mipafox (B). mipafox 221-228 patatin like phospholipase domain containing 6 Gallus gallus 72-75 7082366-3 1982 Included among the paraoxon-resistant esterases is neurotoxic esterase (NTE), which is inhibited in vivo and in vitro by certain organophosphorus compounds, such as mipafox, which cause delayed neurotoxicity. mipafox 165-172 patatin like phospholipase domain containing 6 Gallus gallus 51-70 3579980-8 1987 Mipafox pI50 values obtained from complete titration curves carried out on NTE solubilized in Triton X-100, sodium cholate, or sodium cholate/asolectin were indistinguishable from the value for native enzyme from brain homogenate. mipafox 0-7 patatin like phospholipase domain containing 6 Gallus gallus 75-78 3699331-7 1986 In conclusion, NTE from both species was very similar, with the mipafox I50 for rat NTE within the range of reported values for chicken and human NTE, and the inhibitor parameters of the chicken NTE assay were applicable for the rat NTE assay. mipafox 64-71 patatin like phospholipase domain containing 6 Gallus gallus 84-87 3699331-7 1986 In conclusion, NTE from both species was very similar, with the mipafox I50 for rat NTE within the range of reported values for chicken and human NTE, and the inhibitor parameters of the chicken NTE assay were applicable for the rat NTE assay. mipafox 64-71 patatin like phospholipase domain containing 6 Gallus gallus 84-87 3699331-7 1986 In conclusion, NTE from both species was very similar, with the mipafox I50 for rat NTE within the range of reported values for chicken and human NTE, and the inhibitor parameters of the chicken NTE assay were applicable for the rat NTE assay. mipafox 64-71 patatin like phospholipase domain containing 6 Gallus gallus 84-87 6623525-2 1983 Enzyme activity from chick embryo brain with properties of neurotoxic esterase (NTE, insensitive to 40 microM paraoxon, sensitive to 50 microM mipafox) migrated in a 9S peak. mipafox 143-150 patatin like phospholipase domain containing 6 Gallus gallus 80-83 7082366-3 1982 Included among the paraoxon-resistant esterases is neurotoxic esterase (NTE), which is inhibited in vivo and in vitro by certain organophosphorus compounds, such as mipafox, which cause delayed neurotoxicity. mipafox 165-172 patatin like phospholipase domain containing 6 Gallus gallus 72-75 7278155-4 1981 Because of the commercial unavailability and high toxicity of mipafox, which is usually used as the selective inhibitor for assaying NTE, leptophosoxon was used as an alternative to mipafox. mipafox 62-69 patatin like phospholipase domain containing 6 Gallus gallus 133-136 7278155-5 1981 Results indicated that the NTE fraction of hen brain microsomal PV-hydrolyzing activity is the same target for either mipafox or leptophosoxon. mipafox 118-125 patatin like phospholipase domain containing 6 Gallus gallus 27-30