PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16003537-9 2005 It appears that the change in PO(2), rather than the sustained exposure to a hyperoxic environment, induces the changes in the EPO concentrations and erythropoietic activity. PO-2 30-35 erythropoietin Homo sapiens 127-130 14713116-2 2003 Increased erythropoietin plasma levels and the consequent augmented production of red blood cells is the best known systemic adaptation to reduced oxygen partial pressure (pO2). PO-2 172-175 erythropoietin Homo sapiens 10-24 10746842-9 2000 High EPO values, similarly to ET-1, correlated to low pO2 values. PO-2 54-57 erythropoietin Homo sapiens 5-8 11950137-2 2001 EPO has been the fountainhead in research on pO2-dependent synthesis of proteins. PO-2 45-48 erythropoietin Homo sapiens 0-3 8173014-12 1994 The mechanism of high Epo level in SGA fetuses may involve low pO2 and hemoconcentration. PO-2 63-66 erythropoietin Homo sapiens 22-25 8724724-3 1996 Significant inverse correlations were found between Ua EPO levels and pO2 (r = -0.44, p < 0.002), pH (r = -0.68, p < 0.0001), as well as base deficit (r = -0.56, p < 0.0001). PO-2 70-73 erythropoietin Homo sapiens 55-58 2128766-4 1990 The present in vitro studies show that IL-1 and TNF-alpha, but not IFN-gamma significantly lower the pO2-dependent formation of EPO in HepG2 cultures. PO-2 101-104 erythropoietin Homo sapiens 128-131 8238479-0 1993 Microelectrode measurements of pericellular PO2 in erythropoietin-producing human hepatoma cell cultures. PO-2 44-47 erythropoietin Homo sapiens 51-65 8384444-5 1993 This cyanide- and antimycin-insensitive but hypoxia-sensitive cytochrome b would be an attractive candidate for controlled Epo production in response to pO2. PO-2 153-156 erythropoietin Homo sapiens 123-126 33143240-3 2020 The expression of EPO is strictly regulated by local changes in oxygen partial pressure (pO2) as under-deprived oxygen (hypoxia); the transcription factor hypoxia-inducible factor-2 induces EPO. PO-2 89-92 erythropoietin Homo sapiens 18-21 27406649-7 2016 dose of recombinant human erythropoietin (50 IU kg-1 ) on the isocapnic HVR and HPV in seven male and seven female subjects by exposing them to hypoxia for 20 min (end-tidal PO2 ~50 mmHg) while measuring their ventilation and estimating pulmonary arterial pressure from the maximal velocity of the regurgitant jet over the tricuspid valve during systole (DeltaPmax ) with echocardiography. PO-2 174-177 erythropoietin Homo sapiens 26-40