PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1281830-3 1992 Human endothelial cells (ECs) subjected to hypoxia (PO2 approximately 12-14 Torr) elaborated IL-1 activity into conditioned media in a time-dependent manner; this activity was completely neutralized by an antibody to IL-1 alpha. PO-2 52-55 interleukin 1 alpha Homo sapiens 217-227 2128766-4 1990 The present in vitro studies show that IL-1 and TNF-alpha, but not IFN-gamma significantly lower the pO2-dependent formation of EPO in HepG2 cultures. PO-2 101-104 interleukin 1 alpha Homo sapiens 39-43 1325990-2 1992 Exposure of cells to hypoxia (pO2 approximately 14 torr) followed by reoxygenation led to significant release of IL-1 only from the mononuclear phagocytes. PO-2 30-33 interleukin 1 alpha Homo sapiens 113-117 1325990-3 1992 Elaboration of IL-1 was dependent on the oxygen tension and duration of hypoxia (optimal at lower pO2s, approximately 14-20 torr, and after 9 h), as well as the time in reoxygenation (maximal IL-1 release at 6-9 h). PO-2 98-102 interleukin 1 alpha Homo sapiens 15-19 34917631-9 2021 A weak negative correlation (p < 0.05) between pO2 and serum IL-1beta, IL-12, and IL-33 and between SaO2 and serum IL-33 was noted. PO-2 47-50 interleukin 1 alpha Homo sapiens 61-69