PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33920906-4 2021 Specifically, exposing NK cells to 7-9 days of normoxic culture followed by a pO2 of 1.5% hypoxia led to a highly potent effector phenotype via HIF-1alpha stabilization and upregulation of its target genes, BNIP3, PDK1, VEGF, PKM2, and LDHA. PO-2 78-81 vascular endothelial growth factor A Homo sapiens 220-224 28987998-5 2017 These goals have been successfully met, where an antibody that blocks both murine and human VEGF-A (B20.4.1.1) was found by MS 19F-MRI to produce a strong anti-vascular response and reduce viable tumor pO2 in an HM-7 xenograft model. PO-2 202-205 vascular endothelial growth factor A Homo sapiens 92-98 25166211-4 2014 As expected, hypoxia (1% pO2) further induced HIF-1alpha protein levels along with its target genes VEGF and LOX. PO-2 25-28 vascular endothelial growth factor A Homo sapiens 100-104 11396794-2 2001 Mediated by the hypoxia-inducible transcription factor HIF-1alpha/beta, a reduction in O2 tension (pO2) leads to increased VEGF gene expression in nonmalignant tissues. PO-2 99-102 vascular endothelial growth factor A Homo sapiens 123-127