PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31853788-6 2020 During heat stress, chromium supplementation lowered plasma glucose levels (61.17 +- 1.90 vs. 67.11 +- 1.90 mg/dL), and increased the insulin:glucose ratio (0.39 +- 0.04 vs. 0.27 +- 0.04). Chromium 20-28 insulin Bos taurus 134-141 31865090-5 2020 Moreover, calves that received Cr at levels of 0.05 mg/kg of body weight tended to have higher serum concentrations of glucose and higher ratios of insulin to glucose. Chromium 31-33 insulin Bos taurus 148-155 31865090-10 2020 Moreover, Cr is believed to increase insulin action in insulin-sensitive tissues (i.e., adipose and muscles), resulting in increased farm animal productivity through the improvement of feed intake, growth rate, carcass quality, reproductive parameters and immune functions. Chromium 10-12 insulin Bos taurus 37-44 31865090-10 2020 Moreover, Cr is believed to increase insulin action in insulin-sensitive tissues (i.e., adipose and muscles), resulting in increased farm animal productivity through the improvement of feed intake, growth rate, carcass quality, reproductive parameters and immune functions. Chromium 10-12 insulin Bos taurus 55-62 30277455-0 2019 Effect of chromium supplementation on growth performance, meal pattern, metabolic and antioxidant status and insulin sensitivity of summer-exposed weaned dairy calves. Chromium 10-18 insulin Bos taurus 109-116 31421875-12 2019 Chromium supplementation increased insulin clearance rate and decreased the time to half-maximal concentration and the area under the curve in BBD but not CBD calves. Chromium 0-8 insulin Bos taurus 35-42 31421875-14 2019 However, Cr supplementation increased fecal consistency, decreased respiration rate and days with pneumonia, and increased insulin sensitivity when added to BBD. Chromium 9-11 insulin Bos taurus 123-130 31521355-6 2019 These supplements, particularly chromium, may improve reproductive performance during heat stress by alleviating insulin-mediated damage to the follicle and its enclosed cumulus-oocyte complex. Chromium 32-40 insulin Bos taurus 113-120 29102132-14 2018 Hence, replacing corn by Ca salts of palm oil in the concentrate did not improve insulin sensitivity in Holstein x Gir dairy cows consuming excessive energy during mid to late lactation, whereas Cr-supplementation was effective in improving basal insulin sensitivity in cows not receiving Ca salts of palm oil. Chromium 195-197 insulin Bos taurus 247-254 30259263-5 2019 Insulin sensitivity has been enhanced by Cr in cattle, swine, and broilers. Chromium 41-43 insulin Bos taurus 0-7 28133865-0 2018 The impact of the chromium supplementation on insulin signalling pathway in different tissues and milk yield in dairy cows. Chromium 18-26 insulin Bos taurus 46-53 28133865-9 2018 At day 10 BP, protein content of beta-subunit of insulin receptor (IRbeta) was significantly higher (p 0.05) in muscle, and phosphorylation of insulin receptor substrate 1 at serine 307 (pIRS-1 Ser307 ) was significantly lower (p 0.05) in hepatic tissue of +Cr group. Chromium 262-264 insulin Bos taurus 145-152 28133865-15 2018 In conclusion, chromium modulates insulin signalling pathway in dairy cows, but targeted signalling molecules are different in antepartal then post-partal period, probably due to duration of exposure to chromium and different energy status between those periods. Chromium 15-23 insulin Bos taurus 34-41 9839235-13 1998 This finding was considered to be indirect evidence of enhanced insulin sensitivity in calves fed milk replacer or starter supplemented with Cr. Chromium 141-143 insulin Bos taurus 64-71 22459849-11 2012 Serum insulin concentrations were lower in Cr-supplemented heifers than in controls following glucose infusion. Chromium 43-45 insulin Bos taurus 6-13 22459849-14 2012 Results indicate that Cr Prop supplementation increased tissue sensitivity to insulin in growing heifers. Chromium 22-24 insulin Bos taurus 78-85 22459849-15 2012 Based on insulin sensitivity, Cr requirements (as Cr Prop) of growing heifers can be met by supplementing with 3 mg of Cr/d or 0.47 mg of Cr/kg of DM. Chromium 30-32 insulin Bos taurus 9-16 28378114-0 2017 Effect of Peroral Administration of Chromium on Insulin Signaling Pathway in Skeletal Muscle Tissue of Holstein Calves. Chromium 36-44 insulin Bos taurus 48-55 28378114-1 2017 The objective of this study was to investigate the effects of peroral administration of chromium-enriched yeast on glucose tolerance in Holstein calves, assessed by insulin signaling pathway molecule determination and intravenous glucose tolerance test (IVGTT). Chromium 88-96 insulin Bos taurus 165-172 28378114-4 2017 Chromium supplementation increased protein content of the insulin beta-subunit receptor, phosphorylation of insulin receptor substrate 1 at Tyrosine 632, phosphorylation of Akt at Serine 473, glucose transporter-4, and AMP-activated protein kinase in skeletal muscle tissue, while phosphorylation of insulin receptor substrate 1 at Serine 307 was not affected by chromium treatment. Chromium 0-8 insulin Bos taurus 58-65 28378114-7 2017 Our results indicate that chromium supplementation improves glucose utilization in calves by enhancing insulin intracellular signaling in the skeletal muscle tissue. Chromium 26-34 insulin Bos taurus 103-110 24013931-9 2013 In summary, the current study showed that supplementation of Cr at the level of 1.0 and 1.5 mg of Cr/kg DMI was more effective in improving glucose utilization by increasing potency of insulin hormone and reducing concentration of cortisol hormone. Chromium 61-63 insulin Bos taurus 185-192 23048144-8 2012 This caused an increase in the insulin to glucose ratio (I:G) from 0 to 150 min postinfusion for the Cr-supplemented steers (P = 0.03). Chromium 101-103 insulin Bos taurus 31-38 11132832-9 2000 During the intravenous glucose tolerance test, serum insulin concentrations were increased by supplemental chromium-L-methionine (linear effect of Cr, P < 0.05). Chromium 147-149 insulin Bos taurus 53-60 11132832-14 2000 These data indicate that supplemental Cr, as chromium-L-methionine, increased glucose clearance rate after an insulin infusion and increased the insulin response to an intravenous glucose challenge in growing calves with functioning rumens. Chromium 38-40 insulin Bos taurus 110-117 11132832-14 2000 These data indicate that supplemental Cr, as chromium-L-methionine, increased glucose clearance rate after an insulin infusion and increased the insulin response to an intravenous glucose challenge in growing calves with functioning rumens. Chromium 38-40 insulin Bos taurus 145-152 8880468-4 1996 During glucose tolerance tests, Cr supplementation reduced the ratio of insulin to glucose and reduced plasma concentrations of insulin and triglycerides of primiparous cows during the prepartum period. Chromium 32-34 insulin Bos taurus 72-79 8880468-6 1996 With supplemental Cr, insulin sensitivity was reduced postpartum, particularly for primiparous cows, but insulin sensitivity was increased prepartum. Chromium 18-20 insulin Bos taurus 22-29 8880468-9 1996 Chromium supplementation tended to reduce the ratio of insulin to glucagon. Chromium 0-8 insulin Bos taurus 55-62 8588342-2 1995 The objective of the present study were to test whether blood sera from Cr-supplemented periparturient cows contained immunomodulatory activity for mitogen-stimulated peripheral blood mononuclear cells and, if so, to determine if this activity was explicable by differences in blood profiles of some glucose-regulating hormones (insulin, cortisol, growth hormone, insulin-like growth factor I, and tumor necrosis factor-alpha) between Cr-supplemented and unsupplemented (control) animals. Chromium 72-74 insulin Bos taurus 329-336 8807775-10 1996 However, further Cr addition in the culture medium containing supplemental insulin or cortisol, particularly CrCl3, additively increased (P < 0.05) BPL blastogenic activities with or without con a stimulation. Chromium 17-19 insulin Bos taurus 75-82 8807775-13 1996 However, in vitro study confirmed and extended our previous observations that Cr has an effect on lymphocyte proliferation and this may associate with insulin or cortisol actions. Chromium 78-80 insulin Bos taurus 151-158