PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12759757-0	2003	Parallel down-regulation of chloride channel CLC-K1 and barttin mRNA in the thin ascending limb of the rat nephron by furosemide.	Furosemide	118-128	barttin CLCNK type accessory subunit beta	Rattus norvegicus	56-63	
12759757-2	2003	The aim of the present study was to investigate the influence of the loop diuretic furosemide on the gene expression of the kidney chloride channel ClC-K1 and its recently described functional subunit barttin.	Furosemide	83-93	barttin CLCNK type accessory subunit beta	Rattus norvegicus	201-208	
12759757-9	2003	Under furosemide treatment barttin mRNA was regulated in parallel with ClC-K1 mRNA.	Furosemide	6-16	barttin CLCNK type accessory subunit beta	Rattus norvegicus	27-34	
12759757-12	2003	Microdissection of the inner medullary collecting duct and thin limb of Henle"s loop followed by real-time PCR revealed that CLC-K1 and barttin mRNA regulation in inner medulla was limited to the thin limb; mRNA levels in collecting ducts were not affected by furosemide treatment.	Furosemide	260-270	barttin CLCNK type accessory subunit beta	Rattus norvegicus	136-143	
12759757-13	2003	Our findings imply that during furosemide treatment selective down-regulation of ClC-K1 and barttin mRNAs in thin limb plays a role in maintaining salt and water homeostasis.	Furosemide	31-41	barttin CLCNK type accessory subunit beta	Rattus norvegicus	92-99