PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2319462-0	1990	Intratubular albumin blunts the response to furosemide-A mechanism for diuretic resistance in the nephrotic syndrome.	Furosemide	44-54	albumin	Rattus norvegicus	13-20	
2319462-10	1990	This blunted response presumably occurs because of a reduction in the amount of pharmacologically active drug due to albumin-furosemide binding.	Furosemide	125-135	albumin	Rattus norvegicus	117-124	
2319462-11	1990	Consequently, albumin-furosemide binding in the renal tubule may contribute to the diuretic resistance in nephrotic syndrome.	Furosemide	22-32	albumin	Rattus norvegicus	14-21	
2319462-4	1990	After addition of albumin to furosemide perfusate, fractional loop chloride reabsorption was 45 +/- 1%; a value greater (P less than .01) than that observed in furosemide perfused loop segments, but less (P less than .05) than that observed in control loop segments.	Furosemide	160-170	albumin	Rattus norvegicus	18-25	
2319462-9	1990	Thus, albumin in renal tubule fluid attenuates the effect of furosemide on loop segment chloride reabsorption in the rat.	Furosemide	61-71	albumin	Rattus norvegicus	6-13	
6085642-2	1984	When applied to digitoxin and frusemide, two drugs highly bound to bovine serum albumin, the fraction of drug unbound could be continuously varied over approximately a 30-fold range.	Furosemide	30-39	albumin	Rattus norvegicus	74-87