PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21733846-4 2011 WNK1 and WNK4, members of the WNK (with no lysine [K]) kinase family, either directly or via the downstream SPAK/OSR1 Ste20-type kinases, regulate the furosemide-sensitive NKCC2 and the thiazide-sensitive NCC, kidney-specific CCCs. Furosemide 151-161 WNK lysine deficient protein kinase 4 Homo sapiens 9-13 31496133-0 2019 WNK4 limits distal calcium losses following acute furosemide treatment. Furosemide 50-60 WNK lysine deficient protein kinase 4 Homo sapiens 0-4 31496133-7 2019 Following acute treatment with the loop diuretic, furosemide, which causes hypercalciuria through TAL inhibition, WNK4-/- animals demonstrated increased calcium wasting compared with wild-type controls. Furosemide 50-60 WNK lysine deficient protein kinase 4 Homo sapiens 114-118 31496133-11 2019 Our data show that WNK4, via regulation of TRPV5, limits distal calcium losses following acute treatment with furosemide; however, WNK4 deletion does not affect the chronic renal response to dietary calcium depletion. Furosemide 110-120 WNK lysine deficient protein kinase 4 Homo sapiens 19-23 31928473-0 2020 Re: WNK4 Limits Distal Calcium Losses following Acute Furosemide Treatment. Furosemide 54-64 WNK lysine deficient protein kinase 4 Homo sapiens 4-8