PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35635321-7	2022	One proposed role of NHE3 relates to furosemide-induced urinary acidification.	Furosemide	37-47	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	21-25	
35635321-11	2022	In summary, NHE3 in the TAL plays a role for the sustained acidification effect of furosemide.	Furosemide	83-93	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	12-16	
25362991-12	2015	This intracellular alkalization is mediated through an increased apical NHE3 activity, similar to what we previously observed when tubular transport is inhibited with furosemide.	Furosemide	167-177	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	72-76	
33969697-5	2021	Here we show that levels of Na+-K+-2Cl- cotransporter isoform 2 (NKCC2) and Na+/H+ exchanger isoform 3 (NHE3) are reduced at baseline in SMKOs, accompanied by attenuated natriuretic and diuretic responses to furosemide.	Furosemide	208-218	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	76-102	
33969697-5	2021	Here we show that levels of Na+-K+-2Cl- cotransporter isoform 2 (NKCC2) and Na+/H+ exchanger isoform 3 (NHE3) are reduced at baseline in SMKOs, accompanied by attenuated natriuretic and diuretic responses to furosemide.	Furosemide	208-218	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	104-108	
30484346-3	2019	Furosemide acidifies the urine by increasing acid secretion via the Na+-H+ exchanger 3 (NHE3) in TAL and vacuolar H+-ATPase (V-ATPase) in the distal nephron.	Furosemide	0-10	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	68-86	
30484346-3	2019	Furosemide acidifies the urine by increasing acid secretion via the Na+-H+ exchanger 3 (NHE3) in TAL and vacuolar H+-ATPase (V-ATPase) in the distal nephron.	Furosemide	0-10	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	88-92	
25995110-8	2015	These results suggest that the furosemide-induced H+ secretion is a consequence of a drop in intracellular Na+ concentration, increasing the driving force for NHE3.	Furosemide	31-41	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	159-163	
25995110-9	2015	Intriguingly, in whole animal experiments, furosemide-induced urinary acidification and net acid excretion were markedly reduced by specific NHE3 inhibition.	Furosemide	43-53	solute carrier family 9 (sodium/hydrogen exchanger), member 3	Mus musculus	141-145