PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22591021-1	2012	We wanted to test the hypothesis that treatment with amiloride or spironolactone reduced ambulatory (ABP) and central blood pressure (CBP) and that tubular transport via ENaCgamma and AQP2 was increased after furosemide treatment.	Furosemide	209-219	aquaporin 2	Homo sapiens	184-188	
16464787-0	2006	Increased urinary aquaporin-2 excretion in response to furosemide in patients with chronic heart failure.	Furosemide	55-65	aquaporin 2	Homo sapiens	18-29	
16464787-4	2006	We tested the hypothesis that U-AQP2 increases after a single intravenous dose of furosemide in CHF patients.	Furosemide	82-92	aquaporin 2	Homo sapiens	32-36	
16464787-8	2006	RESULTS: Furosemide increased U-AQP2 (140 %), urine volume (280 %), C(H2O) (95 %) and FE(Na) by a factor of 15 (p<0.008 for all), and also AVP (51 %), PRC, Ang II (86 %) and Aldo (59 %) (p<0.021 for all).	Furosemide	9-19	aquaporin 2	Homo sapiens	32-36	
16095054-0	2005	Urinary excretion of aquaporin-2 after furosemide and felodipine in healthy humans.	Furosemide	39-49	aquaporin 2	Homo sapiens	21-32	
16095054-5	2005	We sought to test the hypotheses that urinary excretion of aquaporin-2 (U-AQP2) increases after a single intravenous dose of furosemide, and that U-AQP2 decreases after a single oral dose of felodipine.	Furosemide	125-135	aquaporin 2	Homo sapiens	59-70	
16095054-5	2005	We sought to test the hypotheses that urinary excretion of aquaporin-2 (U-AQP2) increases after a single intravenous dose of furosemide, and that U-AQP2 decreases after a single oral dose of felodipine.	Furosemide	125-135	aquaporin 2	Homo sapiens	74-78	
16095054-10	2005	RESULTS: Furosemide treatment increased U-AQP2 (202%), urine volume (214%), and FENa by a factor of 11, (p < 0.001 for all), whereas CH2O and GFR were unchanged.	Furosemide	9-19	aquaporin 2	Homo sapiens	42-46	
16095054-17	2005	CONCLUSIONS: Furosemide treatment increased U-AQP2, AVP, and the activity of the renin-angiotensin-aldosterone system.	Furosemide	13-23	aquaporin 2	Homo sapiens	46-50	
10910438-14	2000	The DDAVP-frusemide test revealed that the release of AQP2 into urine is not caused by hypertonicity of tubular fluid.	Furosemide	10-19	aquaporin 2	Homo sapiens	54-58	
22591021-4	2012	The increases in water and sodium absorption via AQP2 and ENaC after furosemide treatment most likely are compensatory phenomena to antagonize water and sodium depletion.	Furosemide	69-79	aquaporin 2	Homo sapiens	49-53