PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2845869-2	1988	During incubation of TNF sensitive mouse tumorigenic fibroblast L-M cells in the presence of rhTNF, hydroxyl radical production detected by the evolution of methane gas from dimethyl sulfoxide increased gradually, at 18 hours reached 1.8 times of that in the absence of rhTNF.	Methane	157-164	tumor necrosis factor	Mus musculus	21-24	
2538230-2	1989	During incubation of TNF sensitive mouse tumorigenic fibroblast L-M cells (2 X 10(7) cells) in the presence of rhTNF (100 U), hydroxyl radical production as detected by the evolution of methane gas from dimethyl sulfoxide increased gradually, at 18 h reaching 1.8 times that in the absence of rhTNF.	Methane	186-193	tumor necrosis factor	Mus musculus	21-24	
30877874-7	2019	Meanwhile, methane treatment suppressed lipopolysaccharide (LPS)-stimulated phosphorylation of MAPKs pathways and its downstream target TNF-alpha and IL-6 in BV2 cells.	Methane	11-18	tumor necrosis factor	Mus musculus	136-145	
26721437-6	2016	Furthermore, methane treatment obviously suppressed the secretion of proinflammatory cytokines including tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-6 (IL-6) and interleukin-1beta (IL-1beta) and increased anti-inflammatory cytokine interleukin-10 (IL-10).	Methane	13-20	tumor necrosis factor	Mus musculus	105-132	
27405597-4	2016	Here we show that methane-rich saline (MS) ip treatment (16 ml/kg) alleviated endotoxin shock, bacteria-induced sepsis and dextran-sulfate-sodium-induced colitis in mice via decreased production of TNF-alpha and IL-6.	Methane	18-25	tumor necrosis factor	Mus musculus	198-207	
26721437-6	2016	Furthermore, methane treatment obviously suppressed the secretion of proinflammatory cytokines including tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-6 (IL-6) and interleukin-1beta (IL-1beta) and increased anti-inflammatory cytokine interleukin-10 (IL-10).	Methane	13-20	tumor necrosis factor	Mus musculus	134-143