PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2845869-2 1988 During incubation of TNF sensitive mouse tumorigenic fibroblast L-M cells in the presence of rhTNF, hydroxyl radical production detected by the evolution of methane gas from dimethyl sulfoxide increased gradually, at 18 hours reached 1.8 times of that in the absence of rhTNF. Methane 157-164 tumor necrosis factor Mus musculus 21-24 2538230-2 1989 During incubation of TNF sensitive mouse tumorigenic fibroblast L-M cells (2 X 10(7) cells) in the presence of rhTNF (100 U), hydroxyl radical production as detected by the evolution of methane gas from dimethyl sulfoxide increased gradually, at 18 h reaching 1.8 times that in the absence of rhTNF. Methane 186-193 tumor necrosis factor Mus musculus 21-24 30877874-7 2019 Meanwhile, methane treatment suppressed lipopolysaccharide (LPS)-stimulated phosphorylation of MAPKs pathways and its downstream target TNF-alpha and IL-6 in BV2 cells. Methane 11-18 tumor necrosis factor Mus musculus 136-145 26721437-6 2016 Furthermore, methane treatment obviously suppressed the secretion of proinflammatory cytokines including tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-6 (IL-6) and interleukin-1beta (IL-1beta) and increased anti-inflammatory cytokine interleukin-10 (IL-10). Methane 13-20 tumor necrosis factor Mus musculus 105-132 27405597-4 2016 Here we show that methane-rich saline (MS) ip treatment (16 ml/kg) alleviated endotoxin shock, bacteria-induced sepsis and dextran-sulfate-sodium-induced colitis in mice via decreased production of TNF-alpha and IL-6. Methane 18-25 tumor necrosis factor Mus musculus 198-207 26721437-6 2016 Furthermore, methane treatment obviously suppressed the secretion of proinflammatory cytokines including tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-6 (IL-6) and interleukin-1beta (IL-1beta) and increased anti-inflammatory cytokine interleukin-10 (IL-10). Methane 13-20 tumor necrosis factor Mus musculus 134-143