PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27405597-0	2016	Methane limit LPS-induced NF-kappaB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3beta-mediated IL-10 expression.	Methane	0-7	interleukin 10	Mus musculus	142-147	
28597201-0	2017	Methane alleviates carbon tetrachloride induced liver injury in mice: anti-inflammatory action demonstrated by increased PI3K/Akt/GSK-3beta-mediated IL-10 expression.	Methane	0-7	interleukin 10	Mus musculus	149-154	
26721437-6	2016	Furthermore, methane treatment obviously suppressed the secretion of proinflammatory cytokines including tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-6 (IL-6) and interleukin-1beta (IL-1beta) and increased anti-inflammatory cytokine interleukin-10 (IL-10).	Methane	13-20	interleukin 10	Mus musculus	271-285	
26721437-6	2016	Furthermore, methane treatment obviously suppressed the secretion of proinflammatory cytokines including tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-6 (IL-6) and interleukin-1beta (IL-1beta) and increased anti-inflammatory cytokine interleukin-10 (IL-10).	Methane	13-20	interleukin 10	Mus musculus	287-292	
30877874-0	2019	Methane ameliorates post-operative cognitive dysfunction by inhibiting microglia NF-kappaB/MAPKs pathway and promoting IL-10 expression in aged mice.	Methane	0-7	interleukin 10	Mus musculus	119-124	
30877874-8	2019	Moreover, methane increased expression of IL-10 in the hippocampus 24 h after surgery, and blockade of IL-10 repressed the protective effect of methane on the cognitive impairments observed in MWM test, decreased microglial activation and the pro-inflammatory cytokine in plasma and hippocampal.	Methane	10-17	interleukin 10	Mus musculus	42-47	
30877874-8	2019	Moreover, methane increased expression of IL-10 in the hippocampus 24 h after surgery, and blockade of IL-10 repressed the protective effect of methane on the cognitive impairments observed in MWM test, decreased microglial activation and the pro-inflammatory cytokine in plasma and hippocampal.	Methane	144-151	interleukin 10	Mus musculus	103-108	
30877874-9	2019	Blockade of IL-10 abrogated the suppression effect of methane on the pro-inflammatory cytokine production and phosphorylation of NF-kappaB and p38MAPK both in hippocampus and in BV2 cells.	Methane	54-61	interleukin 10	Mus musculus	12-17