PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25172945-4	2014	Two recent studies discovered that LRRC8 gene family members encode heteromeric VRAC composed of LRRC8A plus LRRC8B-E, which mediate swelling-activated Cl(-) currents and taurine release in human non-neural cells (Z. Qiu et al.	Taurine	171-178	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	35-40	
28193731-4	2017	We show that, besides the osmolytes taurine and myo-inositol, LRRC8 channels transport the neurotransmitters glutamate, aspartate and gamma-aminobutyric acid (GABA) and the co-activator D-serine.	Taurine	36-43	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	62-67	
26530471-7	2015	Incorporation of the LRRC8D subunit into VRAC substantially increased its permeability for cisplatin and the cellular osmolyte taurine, indicating that LRRC8 proteins form the channel pore.	Taurine	127-134	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	21-26	
25252947-5	2014	Downregulation of volume-sensitive taurine release in RES A2780 cells correlates with reduced expression of the leucine-rich repeat-containing protein 8A (LRRC8A).	Taurine	35-42	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	112-153	
25252947-5	2014	Downregulation of volume-sensitive taurine release in RES A2780 cells correlates with reduced expression of the leucine-rich repeat-containing protein 8A (LRRC8A).	Taurine	35-42	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	155-161	
30318853-1	2018	Shift in the cellular homeostasis of the organic osmolyte taurine has been associated with dysregulation of the volume-regulated anion channel (VRAC) complex, which comprises leucine-rich repeat-containing family 8 members (LRRC8A-E).	Taurine	58-65	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	224-230	
26635246-8	2016	Furthermore, first major insights on the role of LRRC8 proteins in cancer drug resistance and apoptosis and the role of LRRC8D in cisplatin and taurine transport will be summarized.	Taurine	144-151	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	49-54	
25172945-4	2014	Two recent studies discovered that LRRC8 gene family members encode heteromeric VRAC composed of LRRC8A plus LRRC8B-E, which mediate swelling-activated Cl(-) currents and taurine release in human non-neural cells (Z. Qiu et al.	Taurine	171-178	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	97-103	
24790029-7	2014	Taurine flux and regulatory volume decrease also depended on LRRC8 proteins.	Taurine	0-7	leucine rich repeat containing 8 VRAC subunit A	Homo sapiens	61-66