PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7790879-1 1995 The monosialoganglioside GM1 has been shown to possess neurotrophic activity in vitro and in vivo and is now used as an experimental treatment for a variety of neurological disorders and trauma. sialogangliosides 4-24 coenzyme Q10A Mus musculus 25-28 9143118-1 1997 This paper describes the preparation of monosialoganglioside GM1 with sialidase-producing marine bacteria as a microbial biocatalyst. sialogangliosides 40-60 coenzyme Q10A Mus musculus 61-64 1740352-1 1992 We have recently described that large liposomes composed of egg phosphatidylcholine (PC), cholesterol (chol) and monosialoganglioside GM1 show elevated accumulation in the red pulp of the spleen when they are i.v. sialogangliosides 113-133 coenzyme Q10A Mus musculus 134-137 1443421-2 1992 The surface exposure of the monosialoganglioside, GM1, did not differ between the two lines. sialogangliosides 28-48 coenzyme Q10A Mus musculus 50-53 1394121-2 1992 Tissue distribution of sterically stabilized liposomes composed of distearoyl phosphatidylcholine:cholesterol:monosialoganglioside GM1 (10:5:1)-encapsulated 67Ga-Desferal indicates that more than 30% of liposomes still remain in the blood at 24 h after tail vein injection. sialogangliosides 110-130 coenzyme Q10A Mus musculus 131-134 6363631-8 1983 Treatment of the teased fibres with Vibrio cholerae neuraminidase, which is known to reduce polysialogangliosides to the monosialoganglioside GM1, induced cholera toxin binding on the internodal Schwann cell surfaces. sialogangliosides 121-141 coenzyme Q10A Mus musculus 142-145 1995057-9 1991 Compounds which substantially decreased RE uptake of liposomes in vivo, such as monosialoganglioside (GM1) and a novel synthetic lipid derivative of polyethyleneglycol (PEG-PE), also greatly decreased liposome uptake by bone marrow macrophages in a concentration-dependent manner. sialogangliosides 80-100 coenzyme Q10A Mus musculus 102-105 2092039-0 1990 Augmentation of mouse natural killer (NK) activity by GM-1/P, a processed form of monosialoganglioside GM-1. sialogangliosides 82-102 coenzyme Q10A Mus musculus 54-60 2092039-1 1990 We describe the immunomodulatory activity of GM-1/P a processed form of GM-1 (monosialoganglioside) extracted from ox brain, purified and physically modified. sialogangliosides 78-98 coenzyme Q10A Mus musculus 45-51 2092040-0 1990 Enhancement of lymphocyte proliferation and IL-2 receptor expression by a processed form (GM-1/P) of monosialoganglioside GM-1. sialogangliosides 101-121 coenzyme Q10A Mus musculus 90-96 2092040-1 1990 In this study we investigated the ability of GM-1/P, a calcium mediated processed form of monosialoganglioside GM-1, of in vivo augmenting mouse T and B-lymphocyte blastogenesis induced by mitogens. sialogangliosides 90-110 coenzyme Q10A Mus musculus 45-51 3998734-3 1985 Change in the ganglioside composition of the mutant brain from that of the control was observed only in the quaking mutant brain, in which monosialoganglioside GM1 was significantly reduced and GM4 was completely absent. sialogangliosides 139-159 coenzyme Q10A Mus musculus 160-163 2711872-3 1989 Explants chronically grown in a serum-free medium containing the monosialoganglioside GM1 failed to develop dorsal cord selectivity as was previously observed when a mixture of gangliosides was used. sialogangliosides 65-85 coenzyme Q10A Mus musculus 86-89 6520127-5 1984 As a result, the presence of four kinds of monosialoganglioside with a gangliotetraosyl core structure, GM1(NeuAc), GM1(NeuGc), GM1b(NeuAc), and GM1b(NeuGc), were found to exist in the ICR mouse spleen. sialogangliosides 43-63 coenzyme Q10A Mus musculus 104-107 192275-4 1977 Although labeling of the monosialoganglioside GM1 was maximal by 16 h, not all of the GM1 in the intact cells appeared to be accessible to galactose oxidase, since 10 to 12 times more GM1 was labeled when cells were disrupted before incubation with the enzyme. sialogangliosides 25-45 coenzyme Q10A Mus musculus 46-49 20487908-3 1982 It contains sphingosine, glucose, galactose, N-acetylgalactosamine and sialic acid in the molar ratio 1:1:2:1:4 and, upon exhaustive sialidase treatment gives the monosialoganglioside GM1. sialogangliosides 163-183 coenzyme Q10A Mus musculus 184-187 31774647-5 2020 MALDI-IMS uncovered brain-region (2 and 3D) and/or LCB specific accumulations of monosialogangliosides (GMs): GM1, GM2, and GM3 in the hippocampal and cortical amyloid plaques. sialogangliosides 81-102 coenzyme Q10A Mus musculus 110-113 33069891-5 2020 In this article, we demonstrate that monosialoganglioside (GM1) micelles are capable of delivering testosterone into the cytoplasm to specifically activate genomic signaling. sialogangliosides 37-57 coenzyme Q10A Mus musculus 59-62 24765676-5 2014 The application of mono-sialoganglioside GM1 in the slice from GM2/GD2-/- mice, to specifically recover the a-pathway, prevented the increased presynaptic glutamate release and 20 Hz-LTP induction, whereas it could not rescue the impaired NMDAr-dependent LTP. sialogangliosides 19-40 coenzyme Q10A Mus musculus 41-44 14672816-2 2004 Neuraminidase (sialidase) increases levels of GM1, a monosialoganglioside, in these neurons by enzymatic removal of sialic acid from abundant polysialylated gangliosides. sialogangliosides 53-73 coenzyme Q10A Mus musculus 46-49