PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10959557-9	2000	CONCLUSIONS: Rupatadine and loratadine showed similar inhibitory effect on histamine and TNF-alpha release, whereas SR-27417A only exhibited inhibitory effect against TNF-alpha.	Loratadine	28-38	tumor necrosis factor	Homo sapiens	89-98	
30119218-6	2018	The presence of loratadine in endothelial culture efficiently suppressed ox-LDL-induced attachment of monocytes to endothelial cells, production of ROS and vascular adhesion molecules, and induction cytokines including VCAM-1, E-selectin, TNF-alpha, IL-6 and IL-8.	Loratadine	16-26	tumor necrosis factor	Homo sapiens	239-248	
10772385-4	2000	All antihistamines caused a dose-dependent inhibition of TNF-alpha release from HMC-1 cells, with maximal effects at 10(-12) M for azelastine, 10(-9) M for loratadine and cetirizine, and 10(-8) M for ranitidine.	Loratadine	156-166	tumor necrosis factor	Homo sapiens	57-66	
10959557-8	2000	Rupatadine, loratadine and SR-27417A inhibited TNF-alpha release with IC50 2.0+/-0.9 microM, 2.1+/-1.1 M and 4.3+/-0.6 microM, respectively.	Loratadine	12-22	tumor necrosis factor	Homo sapiens	47-56	
10101740-6	1998	Loratadine (0.25-25 microM) induced a significant and dose-dependent decrease of LTB4 production by PMN alone whereas it was up-regulated by TNF-alpha.	Loratadine	0-10	tumor necrosis factor	Homo sapiens	141-150	
10101740-10	1998	Moreover, the TNF-alpha-induced stimulation of LTB4 release that we demonstrated in PMN-HAEC interaction was also inhibited by loratadine.	Loratadine	127-137	tumor necrosis factor	Homo sapiens	14-23