PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11505807-2	2001	This study aimed to determine if one month of therapy with loratadine 10 mg once daily would also induce any decrease in serum levels of soluble ICAM-1 (sICAM-1) or VCAM-1 (sVCAM-1).	Loratadine	59-69	intercellular adhesion molecule 1	Homo sapiens	145-151	
7677235-0	1995	Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM-1 and HLA-DR by nasal epithelial cells.	Loratadine	23-33	intercellular adhesion molecule 1	Homo sapiens	80-86	
11496238-0	2001	Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells.	Loratadine	13-23	intercellular adhesion molecule 1	Homo sapiens	61-94	
11496238-6	2001	OBJECTIVE: We have investigated the effects of desloratadine and loratadine on rhinovirus-induced ICAM-1 expression, mRNA upregulation, and promoter activation.	Loratadine	50-60	intercellular adhesion molecule 1	Homo sapiens	98-104	
11496238-10	2001	RESULTS: Desloratadine and loratadine (0.1-10 micromol/L) inhibited rhinovirus-induced ICAM-1 upregulation in both primary bronchial or transformed (A549) respiratory epithelial cells.	Loratadine	12-22	intercellular adhesion molecule 1	Homo sapiens	87-93	
11496238-12	2001	Desloratadine and loratadine also inhibited ICAM-1 mRNA induction caused by rhinovirus infection in a dose-dependent manner, and they completely inhibited rhinovirus-induced ICAM-1 promoter activation.	Loratadine	3-13	intercellular adhesion molecule 1	Homo sapiens	44-50	
11496238-12	2001	Desloratadine and loratadine also inhibited ICAM-1 mRNA induction caused by rhinovirus infection in a dose-dependent manner, and they completely inhibited rhinovirus-induced ICAM-1 promoter activation.	Loratadine	3-13	intercellular adhesion molecule 1	Homo sapiens	174-180	
9636821-0	1998	Loratadine reduces the expression of ICAM-1.	Loratadine	0-10	intercellular adhesion molecule 1	Homo sapiens	37-43	
9618706-8	1998	Some antihistamines (i.e., levocabastine, terfenadine, loratadine, azelastine and oxatomide) can reduce ICAM-1 expression.	Loratadine	55-65	intercellular adhesion molecule 1	Homo sapiens	104-110	
9360756-2	1997	Loratadine, an H1-blocker, was found to reduce in vitro the expression of ICAM-1 on nasal epithelial cells.	Loratadine	0-10	intercellular adhesion molecule 1	Homo sapiens	74-80	
9360756-3	1997	A double-blind, parallel-group study was carried out during the pollen season to compare the effect of two H1-blockers, cetirizine (10 mg OD) and loratadine (10 mg OD), on the release of soluble ICAM-1 in nasal secretions.	Loratadine	146-156	intercellular adhesion molecule 1	Homo sapiens	195-201	
9383258-8	1997	CONCLUSION: The antiallergic activity of loratadine and cetirizine is documented by their actions on the inflammatory and clinical parameters, especially ICAM-1 modulation.	Loratadine	41-51	intercellular adhesion molecule 1	Homo sapiens	154-160	
9383258-0	1997	Loratadine treatment of rhinitis due to pollen allergy reduces epithelial ICAM-1 expression.	Loratadine	0-10	intercellular adhesion molecule 1	Homo sapiens	74-80	
9383258-6	1997	RESULTS: Loratadine and cetirizine significantly improved symptoms (P < 0.002), significantly reduced eosinophil (P < 0.016) and metachromatic cell (P < 0.01) infiltration, levels of ECP (P < 0.002), EPO (P < 0.006) and histamine (P < 0.01) and ICAM-1 expression on nasal epithelial cells (P < 0.02).	Loratadine	9-19	intercellular adhesion molecule 1	Homo sapiens	263-269