PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11496238-0 2001 Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells. Loratadine 13-23 intercellular adhesion molecule 1 Homo sapiens 61-94 11505807-2 2001 This study aimed to determine if one month of therapy with loratadine 10 mg once daily would also induce any decrease in serum levels of soluble ICAM-1 (sICAM-1) or VCAM-1 (sVCAM-1). Loratadine 59-69 intercellular adhesion molecule 1 Homo sapiens 145-151 11496238-6 2001 OBJECTIVE: We have investigated the effects of desloratadine and loratadine on rhinovirus-induced ICAM-1 expression, mRNA upregulation, and promoter activation. Loratadine 50-60 intercellular adhesion molecule 1 Homo sapiens 98-104 11496238-10 2001 RESULTS: Desloratadine and loratadine (0.1-10 micromol/L) inhibited rhinovirus-induced ICAM-1 upregulation in both primary bronchial or transformed (A549) respiratory epithelial cells. Loratadine 12-22 intercellular adhesion molecule 1 Homo sapiens 87-93 11496238-12 2001 Desloratadine and loratadine also inhibited ICAM-1 mRNA induction caused by rhinovirus infection in a dose-dependent manner, and they completely inhibited rhinovirus-induced ICAM-1 promoter activation. Loratadine 3-13 intercellular adhesion molecule 1 Homo sapiens 44-50 11496238-12 2001 Desloratadine and loratadine also inhibited ICAM-1 mRNA induction caused by rhinovirus infection in a dose-dependent manner, and they completely inhibited rhinovirus-induced ICAM-1 promoter activation. Loratadine 3-13 intercellular adhesion molecule 1 Homo sapiens 174-180 9383258-0 1997 Loratadine treatment of rhinitis due to pollen allergy reduces epithelial ICAM-1 expression. Loratadine 0-10 intercellular adhesion molecule 1 Homo sapiens 74-80 9636821-0 1998 Loratadine reduces the expression of ICAM-1. Loratadine 0-10 intercellular adhesion molecule 1 Homo sapiens 37-43 9383258-8 1997 CONCLUSION: The antiallergic activity of loratadine and cetirizine is documented by their actions on the inflammatory and clinical parameters, especially ICAM-1 modulation. Loratadine 41-51 intercellular adhesion molecule 1 Homo sapiens 154-160 9618706-8 1998 Some antihistamines (i.e., levocabastine, terfenadine, loratadine, azelastine and oxatomide) can reduce ICAM-1 expression. Loratadine 55-65 intercellular adhesion molecule 1 Homo sapiens 104-110 9360756-2 1997 Loratadine, an H1-blocker, was found to reduce in vitro the expression of ICAM-1 on nasal epithelial cells. Loratadine 0-10 intercellular adhesion molecule 1 Homo sapiens 74-80 9360756-3 1997 A double-blind, parallel-group study was carried out during the pollen season to compare the effect of two H1-blockers, cetirizine (10 mg OD) and loratadine (10 mg OD), on the release of soluble ICAM-1 in nasal secretions. Loratadine 146-156 intercellular adhesion molecule 1 Homo sapiens 195-201 9383258-6 1997 RESULTS: Loratadine and cetirizine significantly improved symptoms (P < 0.002), significantly reduced eosinophil (P < 0.016) and metachromatic cell (P < 0.01) infiltration, levels of ECP (P < 0.002), EPO (P < 0.006) and histamine (P < 0.01) and ICAM-1 expression on nasal epithelial cells (P < 0.02). Loratadine 9-19 intercellular adhesion molecule 1 Homo sapiens 263-269 7677235-0 1995 Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM-1 and HLA-DR by nasal epithelial cells. Loratadine 23-33 intercellular adhesion molecule 1 Homo sapiens 80-86