PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16360295-2 2006 We have tested the hypothesis that dexamethasone as well as colostrum feeding influence insulin-dependent glucose metabolism in neonatal calves using the euglycemic-hyperinsulinemic clamp technique. Dexamethasone 35-48 insulin Bos taurus 88-95 23194055-2 2013 HYPOTHESIS: Dexamethasone treatment affects whole body insulin sensitivity. Dexamethasone 12-25 insulin Bos taurus 55-62 27289145-8 2016 Induction by cAMP and dexamethasone was repressed 50% by 100 nM insulin. Dexamethasone 22-35 insulin Bos taurus 64-71 23194055-11 2013 CONCLUSIONS AND CLINICAL IMPORTANCE: Dexamethasone decreases whole body insulin sensitivity and affects glucose and lipid metabolism in early lactating dairy cows. Dexamethasone 37-50 insulin Bos taurus 72-79 16360295-8 2006 Dexamethasone increased plasma glucose, insulin, and glucagon concentrations in the pre-clamp period thus necessitating a reduction in the rate of glucose infusion to maintain euglycemia during the clamp. Dexamethasone 0-13 insulin Bos taurus 40-47 10607937-6 2000 GH, in combination with high concentrations of insulin, DEX, or both, attenuated the ability of insulin or DEX to stimulate leptin expression in vitro. Dexamethasone 56-59 insulin Bos taurus 96-103 14677866-6 2003 Dexamethasone treatment increased (P < or = 0.05) plasma concentrations of glucose, insulin, and glucagon more in colostrum-fed than in formula-fed calves but increased (P < or = 0.05) urea concentrations and decreased (P < or = 0.05) concentrations of NEFA, ACTH, and cortisol independent of colostrum vs. formula feeding. Dexamethasone 0-13 insulin Bos taurus 87-94 14677866-8 2003 Glucagon-to-insulin ratios in DEXA-treated and colostrum-fed calves were decreased (P < 0.05). Dexamethasone 30-34 insulin Bos taurus 12-19 10607937-6 2000 GH, in combination with high concentrations of insulin, DEX, or both, attenuated the ability of insulin or DEX to stimulate leptin expression in vitro. Dexamethasone 107-110 insulin Bos taurus 47-54 9342790-6 1997 DEX, in the presence of insulin, increased lactate production from day 3 to day 7. Dexamethasone 0-3 insulin Bos taurus 24-31 10498047-4 1999 The inhibitory effect of dexamethasone on DNA synthesis was variable depending on the growth factors: significant effect was observed on Hex A and insulin; no significant effect was observed on epidermal growth factor and fetal bovine serum. Dexamethasone 25-38 insulin Bos taurus 147-154 9342790-9 1997 DEX, in the presence of insulin, increased this ratio in the two species after 4 or 5 days. Dexamethasone 0-3 insulin Bos taurus 24-31 8959654-3 1996 Bovine i. m. S-V cells were able to undergo adipose conversion, assessed by emergence of lipid droplets and induction of glycerol-3-phosphate dehydrogenase (GPDH) activity, when treated with 0.25 microM dexamethasone and 0.5 mM 1-methyl-3-isobutylxanthine in a serum-deprived (0.1%) medium containing 850 nM insulin and 1 mM octanoate. Dexamethasone 203-216 insulin Bos taurus 308-324 8586589-6 1995 In addition, treatment with dexamethasone increased (P < .01) serum insulin concentrations. Dexamethasone 28-41 insulin Bos taurus 71-78 8653594-6 1996 Dexamethasone addition to the insulin-supplemented medium significantly increased LPL activity in ovine adipose tissue, whereas it was decreased in bovine adipose tissue on days 4 and 7. Dexamethasone 0-13 insulin Bos taurus 30-37 8653594-7 1996 Moreover, dexamethasone addition to the insulin-supplemented medium did not change G6PDH activity in the two species on day 2, whereas it was increased in bovine and ovine adipose tissue on days 4 and 7. Dexamethasone 10-23 insulin Bos taurus 40-47 7592092-4 1995 The addition of dexamethasone (DEX, 100 nM) to the insulin-supplemented medium increased (P < .05) glucose and acetate utilization by ovine AT. Dexamethasone 16-29 insulin Bos taurus 51-58 7592092-4 1995 The addition of dexamethasone (DEX, 100 nM) to the insulin-supplemented medium increased (P < .05) glucose and acetate utilization by ovine AT. Dexamethasone 31-34 insulin Bos taurus 51-58 23616591-2 2013 This research evaluated whether induction of insulin resistance, using dexamethasone (DEX), in a monovular animal model, the cow, could produce an ovarian phenotype similar to PCOS. Dexamethasone 71-84 insulin Bos taurus 45-52 8138488-6 1994 A higher concentration of DEX (100 nM) potentiated (P < .004) the ability of insulin to attenuate the decrease in G6PDH activity without changing substrate utilization. Dexamethasone 26-29 insulin Bos taurus 80-87 7962275-5 1994 Dexamethasone also abolished the insulin-mediated increase in calf blood flow. Dexamethasone 0-13 insulin Bos taurus 33-40 8138488-5 1994 Dexamethasone (DEX, 10 nM) added to the insulin-supplemented medium decreased (P < .02) glucose utilization, but it did not change acetate utilization or G6PDH activity. Dexamethasone 0-13 insulin Bos taurus 40-47 8138488-5 1994 Dexamethasone (DEX, 10 nM) added to the insulin-supplemented medium decreased (P < .02) glucose utilization, but it did not change acetate utilization or G6PDH activity. Dexamethasone 15-18 insulin Bos taurus 40-47 23616591-2 2013 This research evaluated whether induction of insulin resistance, using dexamethasone (DEX), in a monovular animal model, the cow, could produce an ovarian phenotype similar to PCOS. Dexamethasone 86-89 insulin Bos taurus 45-52 23616591-3 2013 In all of these experiments, DEX induced insulin resistance in cows as shown by increased glucose, insulin, and HOMA-IR (homeostasis model assessment of insulin resistance). Dexamethasone 29-32 insulin Bos taurus 41-48 23616591-3 2013 In all of these experiments, DEX induced insulin resistance in cows as shown by increased glucose, insulin, and HOMA-IR (homeostasis model assessment of insulin resistance). Dexamethasone 29-32 insulin Bos taurus 99-106 23616591-3 2013 In all of these experiments, DEX induced insulin resistance in cows as shown by increased glucose, insulin, and HOMA-IR (homeostasis model assessment of insulin resistance). Dexamethasone 29-32 insulin Bos taurus 99-106 6089573-5 1984 The exposure of cells to insulin reduced ACE activity of cells and their culture supernatants without influencing cell counts or protein content; insulin also partially inhibited the stimulation of ACE activity by dexamethasone or T3. Dexamethasone 214-227 insulin Bos taurus 25-32 6089573-5 1984 The exposure of cells to insulin reduced ACE activity of cells and their culture supernatants without influencing cell counts or protein content; insulin also partially inhibited the stimulation of ACE activity by dexamethasone or T3. Dexamethasone 214-227 insulin Bos taurus 146-153