PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31049140-8 2019 Nox1 and Nox4 mRNA expression was elevated in a dose-dependent manner after culture in 100 nM, 250 nM, 500 nM, or 1000 nM dexamethasone, and the increased expression of NOX1 mRNA was more significant compared with NOX4 mRNA. Dexamethasone 122-135 NADPH oxidase 1 Mus musculus 0-4 31689440-11 2019 Both Dex and Tofa inhibited ileum Nox1, Nox4 and Duox2, but not Nox2 gene expression. Dexamethasone 5-8 NADPH oxidase 1 Mus musculus 34-38 31049140-8 2019 Nox1 and Nox4 mRNA expression was elevated in a dose-dependent manner after culture in 100 nM, 250 nM, 500 nM, or 1000 nM dexamethasone, and the increased expression of NOX1 mRNA was more significant compared with NOX4 mRNA. Dexamethasone 122-135 NADPH oxidase 1 Mus musculus 169-173 31049140-14 2019 Altogether, NOX1- and NOX4-derived ROS plays a pivotal role in high-dose dexamethasone-induced preosteoblast apoptosis by increasing phosphorylated ASK1 and p38 and may be an important mechanism in steroid-induced avascular necrosis of the femoral head (SANFH). Dexamethasone 73-86 NADPH oxidase 1 Mus musculus 12-16