PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3040777-9 1987 Inhibition of IFN-beta synthesis is likely to be responsible for the inhibition of the TNF-induced antiviral state by dexamethasone. Dexamethasone 118-131 interferon beta 1 Homo sapiens 14-22 1988537-5 1991 The synthetic glucocorticoid dexamethasone was previously shown to increase the turnover of IFN-beta mRNA. Dexamethasone 29-42 interferon beta 1 Homo sapiens 92-100 1988537-6 1991 This activity of dexamethasone was clearly observed only in cells expressing IFN-beta mRNA with AU-rich sequences in the 3" UTR. Dexamethasone 17-30 interferon beta 1 Homo sapiens 77-85 2453506-3 1988 A similar decrease in secretion of human IFN-beta was detected in dexamethasone-treated murine C127 cells that carry an IFN expression vector. Dexamethasone 66-79 interferon beta 1 Homo sapiens 41-49 3040777-10 1987 Since IFNs suppress cell growth, inhibition of endogenous IFN-beta synthesis may also be responsible for the amplification by dexamethasone of the growth-stimulating action of TNF and IL-1. Dexamethasone 126-139 interferon beta 1 Homo sapiens 58-66 22358897-7 1997 The IFN-beta expression level reached in the presence of dexamethasone was about three times higher than in the absence of inducer. Dexamethasone 57-70 interferon beta 1 Homo sapiens 4-12 23658644-6 2013 Both dsRNA stimuli evoked early (3 h), concentration-dependent IFN-beta and IFN-lambda1 mRNA expression, which with dsRNA/LyoVec was much greater, and with dsRNA was much less, after 24 h. The effects were inhibited by dexamethasone. Dexamethasone 219-232 interferon beta 1 Homo sapiens 63-71 21832855-9 2011 The poly (I:C)-induced expressions of IFN-beta and ISG20 were inhibited by dexamethasone. Dexamethasone 75-88 interferon beta 1 Homo sapiens 38-46 19452017-10 2009 The poly(I:C)-induced expressions of IL-6 and IL-8 were down-regulated by both DEX and CsA, while the expressions of IFN-beta and TLR3 were suppressed by DEX alone. Dexamethasone 154-157 interferon beta 1 Homo sapiens 117-125 19452017-12 2009 When HCECs were inoculated with HSV-1, DEX led to a decrease in the expression of IL6, IFN-beta, and TLR3, and an extension of plaque formation. Dexamethasone 39-42 interferon beta 1 Homo sapiens 87-95 16670125-5 2006 Our aim was to investigate the effects of dexamethasone on STAT4 activation by IFN-beta and IL-12 in human T cell blasts. Dexamethasone 42-55 interferon beta 1 Homo sapiens 79-87 16670125-6 2006 We report that dexamethasone decreases IL-12-induced STAT4 phosphorylation and IFN-gamma production and enhances IFN-beta-induced STAT4 activation and IL-10 production. Dexamethasone 15-28 interferon beta 1 Homo sapiens 113-121 12944401-8 2003 On the other hand, Dex significantly decreased the endogenous production of interferon-beta, and this cytokine depressed the RANKL-elicited DNA binding of NF-kappaB and AP-1, as well as osteoclast formation. Dexamethasone 19-22 interferon beta 1 Homo sapiens 76-91 12944401-9 2003 Thus, the down-regulation of inhibitory cytokines such as interferon-beta by Dex may allow the osteoclast progenitors to be freed from the suppression of osteoclastogenesis, resulting in an increased number of osteoclasts, as is observed in the early phase of GC-induced osteoporosis. Dexamethasone 77-80 interferon beta 1 Homo sapiens 58-73