PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25323695-4	2014	The BET bromodomains (protein interaction modules that bind acetyl-lysine) have been targeted by potent small-molecule inhibitors, but these inhibitors lack selectivity for individual family members.	N(alpha)-acetyllysine	60-73	delta/notch like EGF repeat containing	Homo sapiens	4-7	
34203690-1	2021	The 3,5-dimethylisoxazole motif has become a useful and popular acetyl-lysine mimic employed in isoxazole-containing bromodomain and extra-terminal (BET) inhibitors but may introduce the potential for bioactivations into toxic reactive metabolites.	N(alpha)-acetyllysine	64-77	delta/notch like EGF repeat containing	Homo sapiens	149-152	
29561307-3	2018	ITH-47 is an acetyl-lysine inhibitor that displaces bromdomain 4 proteins from chromatin by competitively binding to the acetyl-lysine recognition pocket of this bromodomain and extraterminal (BET) BRD protein, thereby preventing transcription of cancer-associated genes and further cell growth.	N(alpha)-acetyllysine	13-26	delta/notch like EGF repeat containing	Homo sapiens	193-196	
29189147-0	2018	Disrupting Acetyl-lysine Interactions: Recent Advance in the Development of BET Inhibitors.	N(alpha)-acetyllysine	11-24	delta/notch like EGF repeat containing	Homo sapiens	76-79	
28277835-3	2017	Proof-of-principle that epigenetic readers are also relevant drug targets was provided by landmark discoveries of selective inhibitors targeting the BET family of acetyl-lysine readers.	N(alpha)-acetyllysine	163-176	delta/notch like EGF repeat containing	Homo sapiens	149-152	
27707886-1	2017	Competitive inhibitors of acetyl-lysine binding to the bromodomains of the BET (bromodomain and extra terminal) family are being developed for the treatment of solid and hematologic malignancies.	N(alpha)-acetyllysine	26-39	delta/notch like EGF repeat containing	Homo sapiens	75-78	
17848202-7	2007	The helix piD forms a portion of the acetyl-lysine binding site, which could be a structural characteristic of Brd2 BD2 and other BET bromodomains.	N(alpha)-acetyllysine	37-50	delta/notch like EGF repeat containing	Homo sapiens	130-133	
23939492-0	2013	BET acetyl-lysine binding proteins control pathological cardiac hypertrophy.	N(alpha)-acetyllysine	4-17	delta/notch like EGF repeat containing	Homo sapiens	0-3	
23939492-2	2013	JQ1, a small molecule inhibitor of bromodomain and extraterminal (BET) acetyl-lysine reader proteins, was identified in a high throughput screen designed to discover novel small molecule regulators of cardiomyocyte hypertrophy.	N(alpha)-acetyllysine	71-84	delta/notch like EGF repeat containing	Homo sapiens	66-69	
21964340-3	2011	Here we use a global proteomic strategy to demonstrate that MLL fusions, as part of SEC and the polymerase-associated factor complex (PAFc), are associated with the BET family of acetyl-lysine recognizing, chromatin "adaptor" proteins.	N(alpha)-acetyllysine	179-192	delta/notch like EGF repeat containing	Homo sapiens	165-168