PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9193876-0 1997 Hydroxylation and demethylation of the tricyclic antidepressant nortriptyline by cDNA-expressed human cytochrome P-450 isozymes. Nortriptyline 64-77 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 102-118 27101231-1 2016 Objectives: To determine relations between drug concentrations and the cytochrome P450-CYP2D6 genotype or phenotype among elderly patients treated with nortriptyline or venlafaxine. Nortriptyline 152-165 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 71-93 21854846-0 2011 Risk assessment of accidental nortriptyline poisoning: the importance of cytochrome P450 for nortriptyline elimination investigated using a population-based pharmacokinetic simulator. Nortriptyline 93-106 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 73-88 21854846-1 2011 It is not possible to make a prospective clinical study that reveals the importance of the nortriptyline metabolising cytochrome P450 (CYP) isoforms (CYP1A2, CYP2C19, CYP2D6, and CYP3A4) in relation to attaining potential toxic nortriptyline concentrations with a possibly fatal outcome. Nortriptyline 91-104 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 118-133 21854846-1 2011 It is not possible to make a prospective clinical study that reveals the importance of the nortriptyline metabolising cytochrome P450 (CYP) isoforms (CYP1A2, CYP2C19, CYP2D6, and CYP3A4) in relation to attaining potential toxic nortriptyline concentrations with a possibly fatal outcome. Nortriptyline 91-104 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 135-138 21854846-1 2011 It is not possible to make a prospective clinical study that reveals the importance of the nortriptyline metabolising cytochrome P450 (CYP) isoforms (CYP1A2, CYP2C19, CYP2D6, and CYP3A4) in relation to attaining potential toxic nortriptyline concentrations with a possibly fatal outcome. Nortriptyline 228-241 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 135-138