PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34464602-5 2021 The main results in adolescent rats showed that nortriptyline induced dose-dependent opposite effects: while 3 mg/kg decreased immobility and increased mBDNF (indicative of an antidepressant-like response), 10 mg/kg decreased exploratory time in the open field and mBDNF (suggestive of an anxiogenic-like response). Nortriptyline 48-61 brain derived neurotrophic factor Mus musculus 152-157 34464602-5 2021 The main results in adolescent rats showed that nortriptyline induced dose-dependent opposite effects: while 3 mg/kg decreased immobility and increased mBDNF (indicative of an antidepressant-like response), 10 mg/kg decreased exploratory time in the open field and mBDNF (suggestive of an anxiogenic-like response). Nortriptyline 48-61 brain derived neurotrophic factor Mus musculus 265-270