PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33756427-7	2021	A common loci rs3181842 (high linkage equilibrium with rs2279345) in CYP2B6 at 19p13.2 were found to be strongly associated with low serum levels of p, p"-DDE in this population in GWAS and were verified by two replications and combined analysis of 2353 subjects (P = 1.00 x 10-22).	Dichlorodiphenyl Dichloroethylene	149-158	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	69-75	
33756427-9	2021	Furthermore, the rs3181842 C allele functionally led to low CYP2B6 expression and activity, resulting in a low metabolic capacity for the formation of p, p"-DDE from p, p"-DDT.	Dichlorodiphenyl Dichloroethylene	151-160	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	60-66	
33756427-10	2021	The study highlighted that CYP2B6 variants were more relevant than environmental exposure to internal p, p"-DDE exposure, which is important information for DDT risk assessments.	Dichlorodiphenyl Dichloroethylene	102-111	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	27-33	
28235828-5	2017	Genome-wide association analyses identified significant maternal loci for p,p"-DDE (P = 7.8 x 10-11) in the CYP2B6 gene and for BDE-28 (P = 3.2 x 10-8) near the SH3GL2 gene, both involved in xenobiotic and lipid metabolism.	Dichlorodiphenyl Dichloroethylene	74-82	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	108-114	
27839851-0	2017	Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p"-dde levels in a population-based sample.	Dichlorodiphenyl Dichloroethylene	79-87	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	41-47	
27839851-6	2017	RESULTS: Evidence for genome-wide significant association with p,p"-DDE levels was observed only for a locus at chromosome 19 corresponding to the CYP2B6 gene (lead SNP rs7260538).	Dichlorodiphenyl Dichloroethylene	63-71	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	147-153	
27839851-9	2017	A whole-genome methylation analysis showed one significant relationship vs. p,p"-DDE levels (p=6.2x10-9) located 7kb downstream the CYP2B6 gene (cg27089200, position chr19:41531976).	Dichlorodiphenyl Dichloroethylene	76-84	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	132-138	
27839851-11	2017	CONCLUSION: Circulating levels of p,p"-DDE were related to genetic variation in the CYP2B6 gene in the general elderly population.	Dichlorodiphenyl Dichloroethylene	34-42	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	84-90