PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34452146-4 2021 It was demonstrated that THC could effectively inhibit the alpha-MSH (melanocyte-stimulating hormone) induced melanin production in B16F10 melanoma cells and the expressions of three key enzymes involved with the biosynthetic process of melanin, tyrosinase (TYR), tyrosinase-related protein 1 (TRP-1), and tyrosinase-related protein 2 (TRP-2), were all significantly reduced. tetrahydrocurcumin 25-28 dopachrome tautomerase Mus musculus 306-334