PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34960104-6 2021 THC upregulated the AdipoR1/R2-APPL1-mediated pathway in the liver and skeletal muscle, which contributes to improved insulin signaling, glucose utilization, and lipid metabolism. tetrahydrocurcumin 0-3 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 Mus musculus 31-36 34960104-7 2021 Furthermore, THC treatment significantly (p < 0.05) preserved islet mass, reduced apoptosis, and restored defective insulin expression in the pancreatic beta-cells of diabetic obese mice, which was accompanied by an elevation of AdipoR1 and APPL1. tetrahydrocurcumin 13-16 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 Mus musculus 241-246