PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30137697-0 2018 Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 response and suppressing the IL-4Ralpha-Jak1-STAT6 and Jagged1/Jagged2 -Notch1/Notch2 pathways in asthmatic mice. tetrahydrocurcumin 0-18 signal transducer and activator of transcription 6 Mus musculus 157-162 30137697-8 2018 RESULTS: Both THC and Cur had beneficial effects on asthmatic mice with regard to nasal symptoms, pathological changes (eosinophils and mucus hyper-production), oxidative stress (malondialdehyde), cytokine production (IL-13), Th17 and cytotoxic T cell subsets, and Th2 signalling pathway (IL-4Ralpha-Jak1-STAT6 and Jagged1/Jagged2-Notch1/Notch2 axis) activity. tetrahydrocurcumin 14-17 signal transducer and activator of transcription 6 Mus musculus 305-310 30137697-9 2018 THC was more effective than Cur in suppressing tissue eosinophilia, mucus production, and IL-4Ralpha/Jak1/STAT6 pathway activity. tetrahydrocurcumin 0-3 signal transducer and activator of transcription 6 Mus musculus 106-111