PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21928294-6 2011 At the molecular levels, the results from Western blot analysis showed that THC significantly down-regulated phosphatidylinositol 3-kinase/protein kinase B and mitogen-activated protein kinase signalings including decreasing the phosphorylation of mammalian target of rapamycin, glycogen synthase kinase 3beta and p70 ribosomal protein S6 kinase. tetrahydrocurcumin 76-79 glycogen synthase kinase 3 beta Homo sapiens 279-309 29976400-7 2018 Glucose uptake and insulin signaling impaired in HepG2 cells incubated with OA were abated by THC treatment, including phosphorylation of the insulin receptor substrate 1 (IRS-1)/phosphoinositide 3-kinase (PI3K)/Akt and downstream signaling pathways, forkhead box protein O1 (FOXO1) and glycogen synthase kinase 3 beta (GSK3beta), which are involved in gluconeogenesis and glycogen synthesis, respectively. tetrahydrocurcumin 94-97 glycogen synthase kinase 3 beta Homo sapiens 287-318 29976400-7 2018 Glucose uptake and insulin signaling impaired in HepG2 cells incubated with OA were abated by THC treatment, including phosphorylation of the insulin receptor substrate 1 (IRS-1)/phosphoinositide 3-kinase (PI3K)/Akt and downstream signaling pathways, forkhead box protein O1 (FOXO1) and glycogen synthase kinase 3 beta (GSK3beta), which are involved in gluconeogenesis and glycogen synthesis, respectively. tetrahydrocurcumin 94-97 glycogen synthase kinase 3 beta Homo sapiens 320-328