PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30423402-0	2019	Tetrahydrocurcumin and octahydrocurcumin, the primary and final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: Role of CYP2E1 and Keap1-Nrf2 pathway.	tetrahydrocurcumin	0-18	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	197-203	
30423402-6	2019	In addition, OHC and THC markedly suppressed the activity and expressions of CYP2E1, and bound to the active sites of CYP2E1.	tetrahydrocurcumin	21-24	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	77-83	
30423402-6	2019	In addition, OHC and THC markedly suppressed the activity and expressions of CYP2E1, and bound to the active sites of CYP2E1.	tetrahydrocurcumin	21-24	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	118-124	
30423402-9	2019	In conclusion, OHC and THC possess favorable hepato-protective effect through restoring antioxidant status, inhibiting CYP2E1 and activating Keap1-Nrf2 pathway, which might represent promising antioxidants for the treatment of APAP-induced hepatotoxicity.	tetrahydrocurcumin	23-26	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	119-125