PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31448474-8	2019	Furthermore, LY294002, a specific inhibitor of PI3K/Akt pathway, attenuated the activation of NK-kappaB and osteogenic differentiation of HASMCs.	hasmcs	138-144	AKT serine/threonine kinase 1	Homo sapiens	52-55	
27035566-7	2016	Furthermore, siRNA-SCARA5 significantly inhibited the phosphorylation of PDGF receptor (PDGFR) beta, AKT and extracellular signal-regulated kinase 1/2 in PDGF-BB-stimulated HASMCs.	hasmcs	173-179	AKT serine/threonine kinase 1	Homo sapiens	101-104	
28415624-5	2017	Mechanically, hypoxia promoted the expression of HIF-1a by PI3K-AKT pathway in HASMCs; HIF-1a further suppressed the expressions of AEG-1, a-SMA and SM22a, and promoted osteopontin (OPN) expression.	hasmcs	79-85	AKT serine/threonine kinase 1	Homo sapiens	64-67	
28716056-10	2017	Furthermore, H2O2 treatment partly improved cell viability and up regulated p-PI3K and p-AKT in HASMCs.	hasmcs	96-102	AKT serine/threonine kinase 1	Homo sapiens	89-92	
28716056-11	2017	CONCLUSIONS: Therefore, we concluded that ISL inhibited the proliferation of HASMCs via attenuating oxidative stress and suppressing PI3K/AKT signaling pathway.	hasmcs	77-83	AKT serine/threonine kinase 1	Homo sapiens	138-141	
16840713-14	2006	CONCLUSIONS: HO-1 and Akt exert codependent cytoprotective effects against OS-induced apoptosis in HASMCs.	hasmcs	99-105	AKT serine/threonine kinase 1	Homo sapiens	22-25	
22085644-6	2012	Moreover, loss of desmin in HASMCs increases the phosphorylation of Akt, inhibitor of kappaB kinase (IKK)-alpha, and inhibitor of kappaB (IkappaB)-alpha proteins, leading to NF-kappaB activation.	hasmcs	28-34	AKT serine/threonine kinase 1	Homo sapiens	68-71	
19726333-10	2009	PTEN overexpression can efficiently inhibit the proliferation of HASMCs possibly through the PI3K/PKB/AKt and P21 pathways.	hasmcs	65-71	AKT serine/threonine kinase 1	Homo sapiens	102-105	
15256478-8	2004	Both ERK1/2 and PI3K/AKt pathways were activated during VEGF-induced HASMCs migration.	hasmcs	69-75	AKT serine/threonine kinase 1	Homo sapiens	21-24