PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19666008-7 2009 Taken together, we demonstrated for the first time that Ang II activates ERK5 via the AT1/PKC/PKD pathway and revealed a critical role of ERK5 in Ang II-induced HASMCs hypertrophy. hasmcs 161-167 angiotensin II receptor type 1 Homo sapiens 86-89 28292711-4 2017 Ang II significantly up-regulated MMP-9 expression and cell migration of HASMCs, which was inhibited by transfection with siRNA of p47phox, Nox2, Nox4, p65, angiotensin II type 1 receptor (AT1R) and pretreatment with the inhibitors of NADPH oxidase, ROS, and NF-kappaB. hasmcs 73-79 angiotensin II receptor type 1 Homo sapiens 157-187 28292711-4 2017 Ang II significantly up-regulated MMP-9 expression and cell migration of HASMCs, which was inhibited by transfection with siRNA of p47phox, Nox2, Nox4, p65, angiotensin II type 1 receptor (AT1R) and pretreatment with the inhibitors of NADPH oxidase, ROS, and NF-kappaB. hasmcs 73-79 angiotensin II receptor type 1 Homo sapiens 189-193