PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22842919-6 2012 Ang II caused the contraction of HASMCs; this effect was reversed by Ang-(1-7). hasmcs 33-39 angiotensinogen Homo sapiens 0-6 22842919-8 2012 Furthermore, Y-27632, an inhibitor of ROCK2, attenuated the Ang II-induced contraction of HASMCs by blocking the RhoA/ROCK2 signaling pathway which is involved in this contraction, and thus may be a major regulator involved in the basal maintenance of contractility in HASMCs. hasmcs 90-96 angiotensinogen Homo sapiens 60-66 19011954-7 2009 Transfecting HASMCs with small interfering RNA (siRNA) to silence ERK5 inhibited Ang II-induced cell hypertrophy. hasmcs 13-19 angiotensinogen Homo sapiens 81-87 8230860-4 1993 The addition of AII to HASMCs induced a rapid, transient increase in intracellular free Ca2+ concentration followed by a lower, sustained phase. hasmcs 23-29 angiotensinogen Homo sapiens 16-19 8230860-6 1993 These results revealed AII receptors in HASMCs to be of the type 1 receptor subtype, which induce Ca2+ mobilization mainly from intracellular Ca2+ stores. hasmcs 40-46 angiotensinogen Homo sapiens 23-26 16713603-7 2006 SalB also significantly inhibited angiotensin II or H2O2-induced MMP-2 mRNA and protein expression and gelatinolytic activity in HASMCs. hasmcs 129-135 angiotensinogen Homo sapiens 34-48 30258282-8 2018 Plasma from AD patients further increased Bax mRNA levels but decreased Bcl2 and alpha-SMA mRNA levels in Ang II-treated HASMCs. hasmcs 121-127 angiotensinogen Homo sapiens 106-112