PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21057728-9 2010 DSPs increased the expression of intercellular adhesion molecule 1 and the release of interleukin-6 in HASMCs, both of which were inhibited by ERK1/2 or NF-kappaB pathway inhibitors. hasmcs 103-109 interleukin 6 Homo sapiens 86-99 20044439-10 2010 The present study profiles the regulatory relationship between LPA and multiple cytokines in vascular SMCs for the first time, provides the first evidence that LPA upregulates IL-6 in vascular SMCs, and reveals the regulatory mechanism of LPA-induced IL-6 production in HASMCs. hasmcs 270-276 interleukin 6 Homo sapiens 251-255 10590238-7 1999 OSM stimulated the release of IL-6 by hASMCs in a dose-dependent way; after a 48-hour exposure, values were 8.5+/-0.7, 29.7+/-3.5, 50.9+/-4.4, and 73.8+/-7.6x10(3) U/mL (n=6) at OSM concentrations of 0, 1, 10, and 100 ng/mL, respectively. hasmcs 38-44 interleukin 6 Homo sapiens 30-34 21829524-5 2011 Adiponectin significantly increased P4Halpha1 mRNA and protein levels in IL-6-stimulated HASMCs in a dose- and time-dependent manner. hasmcs 89-95 interleukin 6 Homo sapiens 73-77 21829524-6 2011 As well, ERK1/2 and Sp1 played a crucial role in the effect of adiponectin upregulating P4Halpha1 expression in IL-6-stimulated HASMCs. hasmcs 128-134 interleukin 6 Homo sapiens 112-116