PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32731540-6 2020 Overall, the most active extracts in inhibiting both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes were ethanol/water and ethanol extracts from seeds (between 31.11 and 53.90%). Ethanol 127-134 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-73 32731540-6 2020 Overall, the most active extracts in inhibiting both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes were ethanol/water and ethanol extracts from seeds (between 31.11 and 53.90%). Ethanol 127-134 acetylcholinesterase (Cartwright blood group) Homo sapiens 75-79 32731540-6 2020 Overall, the most active extracts in inhibiting both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes were ethanol/water and ethanol extracts from seeds (between 31.11 and 53.90%). Ethanol 145-152 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-73 32731540-6 2020 Overall, the most active extracts in inhibiting both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes were ethanol/water and ethanol extracts from seeds (between 31.11 and 53.90%). Ethanol 145-152 acetylcholinesterase (Cartwright blood group) Homo sapiens 75-79 32765630-8 2020 Results: The acetylcholinesterase inhibitory activity from Q. suber cork and corkback ethanol-water extracts was as follows: 62% inhibition with corkback extracts over 0.5 mg/mL and around 49% inhibition in cork extracts over 1.0 mg/mL extracts" concentration. Ethanol 86-93 acetylcholinesterase (Cartwright blood group) Homo sapiens 13-33 31617123-11 2020 Ethanol extract presented a strong inhibitory activity toward p38 and JNK3 MAPKs and AChE activity and also toward TNF-alpha release in human whole blood. Ethanol 0-7 acetylcholinesterase (Cartwright blood group) Homo sapiens 85-89 29804239-6 2018 Donepezil (DON), a centrally acting, reversible and non-competitive acetylcholinesterase (AChE) inhibitor, approved for use in Alzheimer"s disease (AD), may also attenuate EtOH-induced cognitive impairment. Ethanol 172-176 acetylcholinesterase (Cartwright blood group) Homo sapiens 90-94 28427893-0 2017 Study of acetylcholinesterase activity and apoptosis in SH-SY5Y cells and mice exposed to ethanol. Ethanol 90-97 acetylcholinesterase (Cartwright blood group) Homo sapiens 9-29 28427893-6 2017 AChE activity was quantified by spectrophotometry and apoptosis by flow cytometer in SH-SY5Y cells exposed to ethanol. Ethanol 110-117 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 28427893-12 2017 In conclusion, AChE activity and apoptosis were induced in SH-SY5Y cells and mice treated with ethanol, which may indicate that increased AChE may related to apoptosis induced by ethanol. Ethanol 95-102 acetylcholinesterase (Cartwright blood group) Homo sapiens 15-19 28427893-12 2017 In conclusion, AChE activity and apoptosis were induced in SH-SY5Y cells and mice treated with ethanol, which may indicate that increased AChE may related to apoptosis induced by ethanol. Ethanol 179-186 acetylcholinesterase (Cartwright blood group) Homo sapiens 15-19 27668538-8 2016 Our findings revealed that ethanol extract exhibited inhibitory activity against JNK3 and AChE. Ethanol 27-34 acetylcholinesterase (Cartwright blood group) Homo sapiens 90-94 24770900-0 2015 Mild thiamine deficiency and chronic ethanol consumption modulate acetylcholinesterase activity change and spatial memory performance in a water maze task. Ethanol 37-44 acetylcholinesterase (Cartwright blood group) Homo sapiens 66-86 24770900-2 2015 In the present work, the chronic effects of ethanol and its association to a mild thiamine deficiency episode (subclinical model) on neocortical and hippocampal acetylcholinesterase activity were assessed along with their possible association to spatial cognitive dysfunction. Ethanol 44-51 acetylcholinesterase (Cartwright blood group) Homo sapiens 161-181 24770900-3 2015 The results indicate that in the beginning of the neurodegenerative process, before the appearance of brain lesions, chronic ethanol consumption reverses the effects of mild thiamine deficiency on both spatial cognitive performance and acetylcholinesterase activity without having significant effects on any morphometric parameter. Ethanol 125-132 acetylcholinesterase (Cartwright blood group) Homo sapiens 236-256 23380204-4 2013 The strongest 5-lipoxygenase (5-LOX), acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition activities were obtained for the ethanol extract (IC50 values of 6.20, 14.83 and 2.65mg/l, respectively) and the best cytotoxic activity against MCF-7 cells was obtained for the methanol extract (IC50=31mg/l). Ethanol 144-151 acetylcholinesterase (Cartwright blood group) Homo sapiens 38-58 23380204-4 2013 The strongest 5-lipoxygenase (5-LOX), acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition activities were obtained for the ethanol extract (IC50 values of 6.20, 14.83 and 2.65mg/l, respectively) and the best cytotoxic activity against MCF-7 cells was obtained for the methanol extract (IC50=31mg/l). Ethanol 144-151 acetylcholinesterase (Cartwright blood group) Homo sapiens 60-64 23529036-3 2013 The dichloromethane, ethanol and methanol extracts from the leaves of Rauvolfia reflexa showed potential acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities, with IC50 values in the 8.49 to 52.23 g/mL range. Ethanol 21-28 acetylcholinesterase (Cartwright blood group) Homo sapiens 127-131 23550232-1 2013 Acrylonitrile(AN) is a neurotoxin both in animals and humans, but its effects on acetylcholinesterase (AChE) activity remain controversial. Ethanol 14-16 acetylcholinesterase (Cartwright blood group) Homo sapiens 81-101 23550232-1 2013 Acrylonitrile(AN) is a neurotoxin both in animals and humans, but its effects on acetylcholinesterase (AChE) activity remain controversial. Ethanol 14-16 acetylcholinesterase (Cartwright blood group) Homo sapiens 103-107 18573242-9 2008 Ethanol and aqueous extracts of six herbs were found to have high AChE inhibitory activities in a dose-dependent manner. Ethanol 0-7 acetylcholinesterase (Cartwright blood group) Homo sapiens 66-70 7582849-0 1995 Activities of acetylcholinesterase and NA+, K+ -ATP-ase in human erythrocytes after ethanol consumption. Ethanol 84-91 acetylcholinesterase (Cartwright blood group) Homo sapiens 14-34 7582849-1 1995 The influence of ethanol consumption on acetylcholinesterase (AchE) and Na+, K+ -ATP-ase activities was examined in 14 healthy volunteers after 30 minutes of ethanol treatment at a dose 0.6 g/kg of body weight. Ethanol 17-24 acetylcholinesterase (Cartwright blood group) Homo sapiens 40-60 7582849-1 1995 The influence of ethanol consumption on acetylcholinesterase (AchE) and Na+, K+ -ATP-ase activities was examined in 14 healthy volunteers after 30 minutes of ethanol treatment at a dose 0.6 g/kg of body weight. Ethanol 17-24 acetylcholinesterase (Cartwright blood group) Homo sapiens 62-66 7582849-4 1995 In vitro experiments showed that ethanol inhibited the AchE and N+, K+ -ATP-ase activities immediately and in proportion to the concentration of ethanol used. Ethanol 33-40 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 7582849-4 1995 In vitro experiments showed that ethanol inhibited the AchE and N+, K+ -ATP-ase activities immediately and in proportion to the concentration of ethanol used. Ethanol 145-152 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 1407268-0 1992 Differential effects of ethanol on membrane-bound and soluble acetylcholinesterase from sarcoplasmic reticulum membranes. Ethanol 24-31 acetylcholinesterase (Cartwright blood group) Homo sapiens 62-82 1407268-1 1992 The action of ethanol on the activity of membrane-bound and soluble acetylcholinesterase (AChE) in sarcoplasmic reticulum of skeletal muscle has been studied. Ethanol 14-21 acetylcholinesterase (Cartwright blood group) Homo sapiens 68-88 1407268-1 1992 The action of ethanol on the activity of membrane-bound and soluble acetylcholinesterase (AChE) in sarcoplasmic reticulum of skeletal muscle has been studied. Ethanol 14-21 acetylcholinesterase (Cartwright blood group) Homo sapiens 90-94 1407268-2 1992 Treatment of membranes with 2.5-12.5% v/v ethanol produced a slight stimulation of the AChE activity and inhibition at higher concentration. Ethanol 42-49 acetylcholinesterase (Cartwright blood group) Homo sapiens 87-91 1407268-5 1992 Isolated 16 S (A12), 10.5 S (G4) and 4.5 S (G1) forms of AChE were inhibited by ethanol to a similar extent. Ethanol 80-87 acetylcholinesterase (Cartwright blood group) Homo sapiens 57-61 2054485-4 1991 The decrease of acetylcholinesterase activity and the appearance of dystrophic and destructive changes both in the nerve fibers and in neurons was observed in the animals subjected to lasting ethanol effect for 60-90 days. Ethanol 192-199 acetylcholinesterase (Cartwright blood group) Homo sapiens 16-36 35602445-9 2022 The roasted-coffee samples had the best inhibition on tyrosinase (88.26 +- 0.15%, p < 0.05), while the raw fruit-EtOH extract showed the highest inhibition on AChE and BChE enzymes (39.10 +- 2.01%, p < 0.01 and 72.69 +- 0.16%, p < 0.016, respectively). Ethanol 113-117 acetylcholinesterase (Cartwright blood group) Homo sapiens 159-163 20702349-1 1988 The effects of toluene, trichloroethylene and ethanol on membrane acetylcholinesterase (AChE) activity in human and rat intact erythrocytes and erythrocyte ghosts were studied in vitro over a range of concentrations (300-3000 ppm) and at three different incubation temperatures (37, 15 and 5 degrees C). Ethanol 46-53 acetylcholinesterase (Cartwright blood group) Homo sapiens 66-86 20702349-1 1988 The effects of toluene, trichloroethylene and ethanol on membrane acetylcholinesterase (AChE) activity in human and rat intact erythrocytes and erythrocyte ghosts were studied in vitro over a range of concentrations (300-3000 ppm) and at three different incubation temperatures (37, 15 and 5 degrees C). Ethanol 46-53 acetylcholinesterase (Cartwright blood group) Homo sapiens 88-92 3767274-0 1986 Effect of ethanol on erythrocyte acetylcholinesterase activity. Ethanol 10-17 acetylcholinesterase (Cartwright blood group) Homo sapiens 33-53 3767274-3 1986 In vitro experiments showed that ethanol inhibited the AchE activity immediately and in proportion to the concentration of ethanol used. Ethanol 33-40 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 3767274-3 1986 In vitro experiments showed that ethanol inhibited the AchE activity immediately and in proportion to the concentration of ethanol used. Ethanol 123-130 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 3767274-5 1986 Incubation of normal red cells with ethanol for 15 h, followed by washing, showed also that AchE activity was inhibited by the previous exposure to ethanol and that washing did not reduce the inhibitory effect. Ethanol 36-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 92-96 3767274-5 1986 Incubation of normal red cells with ethanol for 15 h, followed by washing, showed also that AchE activity was inhibited by the previous exposure to ethanol and that washing did not reduce the inhibitory effect. Ethanol 148-155 acetylcholinesterase (Cartwright blood group) Homo sapiens 92-96 3468911-3 1986 Of the alcohols studied, only ethanol had a slight AchE inhibiting effect at +37 degrees C. The decrease in the incubation temperature increased the AchE inhibiting potency of aromatic hydrocarbons more than that of chlorinated aliphatic hydrocarbons and alcohols. Ethanol 30-37 acetylcholinesterase (Cartwright blood group) Homo sapiens 51-55 3468911-3 1986 Of the alcohols studied, only ethanol had a slight AchE inhibiting effect at +37 degrees C. The decrease in the incubation temperature increased the AchE inhibiting potency of aromatic hydrocarbons more than that of chlorinated aliphatic hydrocarbons and alcohols. Ethanol 30-37 acetylcholinesterase (Cartwright blood group) Homo sapiens 149-153 1029908-1 1976 Water, saline and ethanol extracts of Eugenia caryophyllus inhibited brain acetylcholinesterase (AchE) activity. Ethanol 18-25 acetylcholinesterase (Cartwright blood group) Homo sapiens 75-95 1029908-1 1976 Water, saline and ethanol extracts of Eugenia caryophyllus inhibited brain acetylcholinesterase (AchE) activity. Ethanol 18-25 acetylcholinesterase (Cartwright blood group) Homo sapiens 97-101 33922645-8 2021 Moreover, ethanol extract of kinkor (Ferulago stellata) demonstrated IC50 values of 1.772 mug/mL against acetylcholinesterase (AChE), 33.56 +- 2.96 mug/mL against alpha-glycosidase, and 0.639 mug/mL against alpha-amylase enzyme respectively. Ethanol 10-17 acetylcholinesterase (Cartwright blood group) Homo sapiens 105-125 33922645-8 2021 Moreover, ethanol extract of kinkor (Ferulago stellata) demonstrated IC50 values of 1.772 mug/mL against acetylcholinesterase (AChE), 33.56 +- 2.96 mug/mL against alpha-glycosidase, and 0.639 mug/mL against alpha-amylase enzyme respectively. Ethanol 10-17 acetylcholinesterase (Cartwright blood group) Homo sapiens 127-131 32720328-10 2021 Similarly, the ethanol extract (IC50 = 13.83 microg/ml) exhibited the highest acetylcholinesterase inhibitory activity, while the dichloromethane extract showed the highest butyrylcholinesterase inhibitory activity. Ethanol 15-22 acetylcholinesterase (Cartwright blood group) Homo sapiens 79-99 32720328-11 2021 All the extracts exhibited antioxidant properties and inhibitory effects against butyrylcholinesterase and acetylcholinesterase; however, ethanol extracts showed better activity. Ethanol 138-145 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-127