PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26758662-4 2016 To examine this, we used a combination of whole-cell patch-clamp recordings and optogenetics to demonstrate that ethanol potently depresses both MSN- and fast-spiking interneuron (FSI)-MSN GABAergic synaptic transmission in the DLS. Ethanol 113-120 moesin Homo sapiens 145-148 26758662-4 2016 To examine this, we used a combination of whole-cell patch-clamp recordings and optogenetics to demonstrate that ethanol potently depresses both MSN- and fast-spiking interneuron (FSI)-MSN GABAergic synaptic transmission in the DLS. Ethanol 113-120 moesin Homo sapiens 185-188 26758662-5 2016 Concentrating on the powerfully inhibitory FSI-MSN synapse, we further show that acute exposure of ethanol (50 mM) to striatal slices activates delta opioid receptors that reside on FSI axon terminals and negatively couple to adenylyl cyclase to induce a long-term depression of GABA release onto both direct and indirect pathway MSNs. Ethanol 99-106 moesin Homo sapiens 47-50