PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31941605-0 2020 Gracillin inhibits apoptosis and inflammation induced by lipopolysaccharide (LPS) to alleviate cardiac injury in mice via improving miR-29a. gracillin 0-9 microRNA 29a Mus musculus 132-139 31941605-4 2020 First, we found that GRA treatments markedly up-regulated the expression of miR-29a in cardiomyocytes. gracillin 21-24 microRNA 29a Mus musculus 76-83 31941605-11 2020 We also found that miR-29a expression was highly reduced in hearts of LPS-treated mice but was rescued by GRA pretreatment. gracillin 106-109 microRNA 29a Mus musculus 19-26 31941605-13 2020 Of note, the protective effects of GRA on LPS-injured cardiac tissues were significantly abrogated by miR-29a suppression. gracillin 35-38 microRNA 29a Mus musculus 102-109 31941605-14 2020 In conclusion, our findings demonstrated that GRA exerted an effective role against LPS-induced acute cardiac injury through impeding apoptosis and inflammation regulated by miR-29a. gracillin 46-49 microRNA 29a Mus musculus 174-181