PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2767140-6 1989 Most of the substances acted as reversible, competitive inhibitors with KI in the range of 10(-6)-10(-3) M. The substrate analogues had Km values between (1.2-2.2) X 10(-4) M. The data allow the following main conclusions: (1) The quaternary trimethylammonium group of ACh is of high importance for substrate binding to AChE. quaternary trimethylammonium 231-259 acetylcholinesterase (Cartwright blood group) Homo sapiens 320-324