PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16855053-3 2006 Using 16 individual human liver microsomes (HLMs), a strong correlation was observed with endosulfan sulfate formation and S-mephenytoin N-demethylase activity of CYP2B6 (r(2) = 0.79), whereas a moderate correlation with testosterone 6 beta-hydroxylase activity of CYP3A4 (r(2) = 0.54) was observed. endosulfan sulfate 90-108 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 163-169 16581944-5 2006 Correlation analysis between the known P450 enzyme activities and the rate of the formation of endosulfan sulfate in the 14 human liver microsomes showed that alpha-endosulfan metabolism is significantly correlated with CYP2B6-mediated bupropion hydroxylation and CYP3A-mediated midazolam hydroxylation, and that beta-endosulfan metabolism is correlated with CYP3A activity. endosulfan sulfate 95-113 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 220-226