PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19521778-3 2009 Memantine (0.1-2 muM) suppressed neuronal apoptosis evoked by staurosporine in 7 DIV cortical neurons, whereas other antagonists of NMDA receptor, MK-801 (1 muM) and AP-5 (100 muM) were ineffective. Memantine 0-9 latexin Homo sapiens 17-20 25982509-10 2015 The use-dependent NMDAR inhibitor, memantine (100muM), reduced numbers and proliferation of Meg-01 cells to less than 20% of controls (IC50 20muM and 36muM, respectively). Memantine 35-44 latexin Homo sapiens 49-52 25239809-5 2015 We report that extrasynaptic NMDAR blocker memantine, reduced in a dose-dependent manner cortically induced NMDA excitatory currents in striatal neurons (recorded in zero-Mg(++) plus DNQX 10 muM). Memantine 43-52 latexin Homo sapiens 191-194 25239809-6 2015 Moreover, memantine (2-4 muM) significantly reduced the NMDAR-dependent membrane potential oscillations called up and down states. Memantine 10-19 latexin Homo sapiens 25-28 25239809-10 2015 After severing connections between compartments, active striatal neurons in the presence of memantine (1 muM) and CNQX (10 muM) were predominantly fast spiking interneurons (FSI). Memantine 92-101 latexin Homo sapiens 105-108 23727219-4 2013 Memantine (10 muM) caused robust inhibition of whole-cell (synaptic and extrasynaptic) NMDARs activated by NMDA at a high concentration or a long duration, low concentration. Memantine 0-9 latexin Homo sapiens 14-17