PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23276665-9	2013	Since donepezil and memantine have been widely used for treating patients of Alzheimer"s disease, these results also suggest that cognitive deficits in PS1/APP mice assessed in the Y-maze and Morris water maze tasks are a useful animal model for evaluating novel Alzheimer"s disease therapeutics.	Memantine	20-29	presenilin 1	Homo sapiens	152-159	
18615702-3	2008	In this study, we assessed whether NMDA receptor inhibition by memantine in transgenic mice expressing human amyloid-beta precursor protein (APP) and presenilin 1 (PS1) is associated with cognitive benefit and amyloid burden reduction by using object recognition, micromagnetic resonance imaging (micro MRI), and histology.	Memantine	63-72	presenilin 1	Homo sapiens	150-162	
18615702-3	2008	In this study, we assessed whether NMDA receptor inhibition by memantine in transgenic mice expressing human amyloid-beta precursor protein (APP) and presenilin 1 (PS1) is associated with cognitive benefit and amyloid burden reduction by using object recognition, micromagnetic resonance imaging (micro MRI), and histology.	Memantine	63-72	presenilin 1	Homo sapiens	164-167