PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8886398-7	1996	Memantine (0.3-30 microM) blocked L-glutamate (100 microM)-mediated currents in a concentration-dependent manner in NR1a/NR2A, NR1a/NR2B and NR1a/NR2D transfected cells with IC50 values (at -70 mV) of 0.93 +/- 0.15 microM, 0.82 +/- 0.12 microM and 0.47 +/- 0.06 microM (mean +/- s.c. mean), respectively.	Memantine	0-9	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	Mus musculus	146-150	
23641686-6	2013	A recent study demonstrated that NR2C- and/or NR2D-containing NMDARs are the primary targets of memantine, a drug that is widely prescribed to treat Alzheimer"s disease.	Memantine	96-105	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	Mus musculus	46-50	
23641686-7	2013	Our laboratory demonstrated that memantine prevents the loss of retinal ganglion cells (RGCs) in GLAST glutamate transporter knockout mice, a model of normal tension glaucoma (NTG), suggesting that NR2D-containing receptors may be involved in RGC loss in NTG.	Memantine	33-42	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	Mus musculus	198-202