PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34121969-0 2021 Memantine shifts cancer cell metabolism via AMPK1/2 mediated energetic switch in A549 lung cancer cells. Memantine 0-9 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 44-51 34121969-6 2021 Our results suggest that memantine activates AMPK1/2 significantly (p=0.039 and p=0.0105) that led cells through apoptosis and autophagy by decreasing cancer cell metabolism regulators like HIF1A, B-catenin and PKM as the consequence of this energetic shift. Memantine 25-34 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 45-52