PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26868507-7 2016 Furthermore, simvastatin + ezetimibe increased catalase activity. Simvastatin 13-24 catalase Homo sapiens 47-55 14755972-4 2003 Under treatment with simvastatin we obtained a significant decrease of total cholesterol (p < 0.0001) and an improvement of enzymatic antioxidant parameters: superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT). Simvastatin 21-32 catalase Homo sapiens 223-231 14755972-4 2003 Under treatment with simvastatin we obtained a significant decrease of total cholesterol (p < 0.0001) and an improvement of enzymatic antioxidant parameters: superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT). Simvastatin 21-32 catalase Homo sapiens 233-236 14755972-5 2003 In conclusion, simvastatin therapy determines a significant decrease in SOD, GPx, CAT, and an increase in CAT/SOD and GPx/SOD ratios. Simvastatin 15-26 catalase Homo sapiens 82-85 14755972-5 2003 In conclusion, simvastatin therapy determines a significant decrease in SOD, GPx, CAT, and an increase in CAT/SOD and GPx/SOD ratios. Simvastatin 15-26 catalase Homo sapiens 106-109 35146420-4 2022 This study is the first to show the molecular binding of simvastatin to catalase through molecular docking analysis. Simvastatin 57-68 catalase Homo sapiens 72-80 35146420-7 2022 The activity of catalase and superoxide dismutase (SOD) both increased significantly in oxidatively stressed HepG2 cells after the treatment with simvastatin (10 muM, 24 h). Simvastatin 146-157 catalase Homo sapiens 16-24 35146420-9 2022 Furthermore, a significant increase in the antioxidant enzymes such as Catalase, SOD, and reduced glutathione (GSH) was noted after simvastatin treatment in the HFD model. Simvastatin 132-143 catalase Homo sapiens 71-79 17479860-12 2006 The activities of antioxidants enzymes (CAT, GSH-Px, SOD) significantly increased after 4 weeks therapy in patients treated with atorvastatin and simvastatin. Simvastatin 146-157 catalase Homo sapiens 40-43 22694979-6 2012 CAT activity was higher in the simvastatin group (median 3.98 U ml vs. 3.19, p = 0.023). Simvastatin 31-42 catalase Homo sapiens 0-3 24023786-11 2013 Simvastatin significantly induced cellular reactive oxygen species levels along with expression of pro- and anti-oxidative genes such as Nox2, and MnSOD and catalase, respectively. Simvastatin 0-11 catalase Homo sapiens 157-165