PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19842842-0 2009 Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats. Simvastatin 0-11 GATA binding protein 6 Rattus norvegicus 36-42 19842842-3 2009 The aim of present study was to investigate the expression of GATA-6 gene in experimental pulmonary hypertensive rats and explore the effect of regulation of GATA-6 expression by simvastatin on pulmonary vascular remodeling. Simvastatin 179-190 GATA binding protein 6 Rattus norvegicus 158-164 19842842-8 2009 The level of GATA-6 mRNA and protein were markedly decreased in these pneumonectomy and MCT-treated rats, and they were significantly up-regulated in these rats after receiving simvastatin. Simvastatin 177-188 GATA binding protein 6 Rattus norvegicus 13-19 19842842-9 2009 These results indicate that the development and progression of pulmonary hypertension is prevented by simvastatin by up-regulating GATA-6 expression in the lung tissue. Simvastatin 102-113 GATA binding protein 6 Rattus norvegicus 131-137