PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26565813-8 2016 Furthermore, simvastatin significantly inhibited MAPK/ERK pathway by dephosphorylating sequential cascades such as c-Raf, MEK1/2 and ERK1/2. Simvastatin 13-24 zinc fingers and homeoboxes 2 Homo sapiens 117-120 23045963-8 2012 Our results thus suggest that simvastatin and R115777 may exert, in susceptible lung cancer cell phenotypes, a pro-apoptotic and anti-proliferative activity, which appears to be mediated by inhibition of the Ras/Raf/MEK/ERK signalling cascade. Simvastatin 30-41 zinc fingers and homeoboxes 2 Homo sapiens 212-215 15262179-0 2004 Simvastatin suppresses coronary artery endothelial tube formation by disrupting Ras/Raf/ERK signaling. Simvastatin 0-11 zinc fingers and homeoboxes 2 Homo sapiens 84-87 15262179-12 2004 In conclusion, simvastatin-induced Ras/Raf/ERK inactivation is a potent signal in the anti-angiogenic phenotype of HCECs. Simvastatin 15-26 zinc fingers and homeoboxes 2 Homo sapiens 39-42 15262179-13 2004 Fpp counteracted simvastatin-induced Ras/Raf/ERK inactivation. Simvastatin 17-28 zinc fingers and homeoboxes 2 Homo sapiens 41-44